Single enantiomer synthesis of α-(trifluoromethyl)-β-lactam
- Václav Jurčík
- Ra M. Z. Slawin
- Beilstein J. Org Chem
DOIAbstract
enantiomeric resolution; organofluorine building blocks; α-(trifluoromethyl)-β-lacta
enantiomeric resolution; organofluorine building blocks; α-(trifluoromethyl)-β-lacta
The reduction of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-one with growing cultures of G...
Different catalytic approaches have been applied to new -lactams preparations. olefin metathesis has...
Ethyl trans-3-(trifluoromethyl)pyroglutamate 1 is synthesized in excellent yield; racemic 1 is enzym...
The first synthesis of alpha-(trifluoromethyl)-beta-lactam ((S)-1) is reported. The route starts fro...
Asymmetric cyclocondensation of N-sulfonylimines with fluoroacetic acid promoted by isothiourea cata...
The combination of a practical and highly enantioselective organocatalytic reaction, which allows th...
An efficient four-step biotransformation-mediated synthesis of (1S)-1-(2,6-dichloro-3-fluorophenyl)e...
A general method for the enantioselective synthesis of carbo- and heterocyclic carbonyl compounds be...
Trans N-benzyl-3-trifluoromethyl-2-ethoxycarbonylaziridine 2a, easily obtainable in enantiopure form...
The organolithium species addition to 2-hydroxymethyl fluorinated oxazolidines (Fox) provides a high...
One of the goals of diversity-oriented synthesis is to achieve the structural diversity of obtained ...
The demand for chiral synthetic compounds has led the field of asymmetric catalysis to discover, exp...
The preparation of both enantiomers of 3,3,3-trifluoro-2-methylpropanoic acid by a lipase mediated k...
The enantioselective synthesis of a N-benzyl substituted β-lactam, a precursor for carbapenem antibi...
The tricyclic beta-lactam 5 has been synthesized both in racemic and enantiopure form starting from ...
The reduction of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-one with growing cultures of G...
Different catalytic approaches have been applied to new -lactams preparations. olefin metathesis has...
Ethyl trans-3-(trifluoromethyl)pyroglutamate 1 is synthesized in excellent yield; racemic 1 is enzym...
The first synthesis of alpha-(trifluoromethyl)-beta-lactam ((S)-1) is reported. The route starts fro...
Asymmetric cyclocondensation of N-sulfonylimines with fluoroacetic acid promoted by isothiourea cata...
The combination of a practical and highly enantioselective organocatalytic reaction, which allows th...
An efficient four-step biotransformation-mediated synthesis of (1S)-1-(2,6-dichloro-3-fluorophenyl)e...
A general method for the enantioselective synthesis of carbo- and heterocyclic carbonyl compounds be...
Trans N-benzyl-3-trifluoromethyl-2-ethoxycarbonylaziridine 2a, easily obtainable in enantiopure form...
The organolithium species addition to 2-hydroxymethyl fluorinated oxazolidines (Fox) provides a high...
One of the goals of diversity-oriented synthesis is to achieve the structural diversity of obtained ...
The demand for chiral synthetic compounds has led the field of asymmetric catalysis to discover, exp...
The preparation of both enantiomers of 3,3,3-trifluoro-2-methylpropanoic acid by a lipase mediated k...
The enantioselective synthesis of a N-benzyl substituted β-lactam, a precursor for carbapenem antibi...
The tricyclic beta-lactam 5 has been synthesized both in racemic and enantiopure form starting from ...
The reduction of (Z)-3-fluoro-4-phenyl-1-(p-tolylsulphonyl)but-3-en-2-one with growing cultures of G...
Different catalytic approaches have been applied to new -lactams preparations. olefin metathesis has...
Ethyl trans-3-(trifluoromethyl)pyroglutamate 1 is synthesized in excellent yield; racemic 1 is enzym...
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