Articles © The authors | Journal compilation © Cardiol Res and Elmer Press ™ | www.cardiologyres.org Myocardial Contrast Echocardiography in the Evaluation of

Myocardial contrast echocardiography (MCE) has an established role in left ventricular assessment by improving the ventricular opacification and endocardial border definition especially in pa-tients with sub-optimal echocardiographic images. With advances in cardiac ultrasound imaging technology and the development of new contrast agents, the clinical utility of this technique has greatly expanded to include assessment of coronary reperfusion in the set-ting of acute myocardial infarction, determination of myocardial viability within infarct zones as well as assessment of coronary microcirculation and flow reserve in patients with microvascular coronary disease. Improvements in image quality with intravenous contrast agents can facilitate image acquisition and enhance delin-eation of regional wall motion abnormalities at peak levels of exer-cise. Numerous studies have confirmed the clinical utility of con-trast enhancement during echocardiographic studies, particularly in patients undergoing stress testing. In this paper, we explore the evi-dence in support of MCE and its potential clinical applications. Our review aims to summarize (1) the basic principles of myocardial contrast echocardiography including recent advances in the ultra-sound technology and contrast agents (2) its clinical applications in the diagnosis of cardiovascular diseases and finally, (3) its potential role in risk stratification and assessment of microvascular perfusion in patients with hypertensive heart disease