Effect of Moderate Hypothermia on Lipid Peroxidation in Canine Brain Tissue After

of moderate hypothermia (30°C to 32°C) initiated after resus-citation on the scavenging systems of free radicals and lipid peroxidation in canine brain tissue after cardiac arrest and resuscitation. Methods Twenty-one dogs were divided into four groups: group A, nonischemic controls (shams) (n=4); group B, 15-minute cardiac arrest without reperfusion (n=4); group C, 15-minute cardiac arrest and standard resuscitation (n=6); and group D, 15-minute cardiac arrest and hypothermic resuscitation (n=7). During the period of 10 to 120 minutes after resuscitation, brain temperature and core temperature in group D remained at 30°C to 32°C and were 4°C to 5°C lower than in group C. For each dog, a sample of right parietal cerebral cortex was obtained from group A, group B, or from group C and group D at 2 hours after resuscitation. Th