Add to ORKGWe studied the β-catenin immunohistochemical profile in tumors expressing shadow cells: pilomatricoma, 10 cases; calcifying odontogenic cyst, 6 cases; and craniopharyngioma, 9 cases. There was strong membranous, cytoplasmic, and nuclear staining of the immature basaloid cells in all of these tumors. Shadow cells were negative in all tumors. It has been documented that rising levels of free β-catenin drive the formation of complexes with T-cell factor/lymphoid enhancer factor (TCF-Lef) and up-regulate the wingless-Wnt cell-cell signals. The end result is an abnormality of β-catenin degradation and, thus, a buildup of free β-catenin in the cytoplasm and/or nucleus, resulting in the stimulation of cellular proliferation and/or inhibition of ce...
β-catenin is involved in cell adhesion through catenin-cadherin complexes and as a transcriptional r...
Background beta-catenin, a 92 kDa protein that binds to the cytoplasmic tail of E-cadherin, has an e...
The molecular events that precede the development of osteosarcoma, the most common primary malignanc...
<p>β-catenin was highly expressed in tumors. (A) In most cases, β-catenin expression was primarily l...
Background: β-catenin gene mutations have been reported in vast majority of pilomatrixomas (PMXs). β...
In epithelial cells -catenin plays a critical role as a component of the cell-cell adhe-sion apparat...
beta-Catenin plays a fundamental role in the regulation of the E-cadherin-catenin cell adhesion comp...
Activation of the Wnt/wingless signalling cascade is a key mechanism in developmental morphogenesis,...
Cataloged from PDF version of article.β-catenin is involved in both cell-cell interactions and wnt p...
International audienceDesmoid tumors (TDs) are derived from mesenchymal stem cells and their pathoge...
Dentinogenic ghost cell tumor (DGCT) is considered as a neoplastic counterpart of the calcifying odo...
INTRODUCTION: Although altered regulation of the Wnt pathway via beta-catenin is a frequent event in...
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and accounts for about 5% ...
# The Author(s) 2010. This article is published with open access at Springerlink.com Abstract In can...
Ankara : Department of Molecular Biology and Genetics and Institute of Engineering and Science of Bi...
β-catenin is involved in cell adhesion through catenin-cadherin complexes and as a transcriptional r...
Background beta-catenin, a 92 kDa protein that binds to the cytoplasmic tail of E-cadherin, has an e...
The molecular events that precede the development of osteosarcoma, the most common primary malignanc...
<p>β-catenin was highly expressed in tumors. (A) In most cases, β-catenin expression was primarily l...
Background: β-catenin gene mutations have been reported in vast majority of pilomatrixomas (PMXs). β...
In epithelial cells -catenin plays a critical role as a component of the cell-cell adhe-sion apparat...
beta-Catenin plays a fundamental role in the regulation of the E-cadherin-catenin cell adhesion comp...
Activation of the Wnt/wingless signalling cascade is a key mechanism in developmental morphogenesis,...
Cataloged from PDF version of article.β-catenin is involved in both cell-cell interactions and wnt p...
International audienceDesmoid tumors (TDs) are derived from mesenchymal stem cells and their pathoge...
Dentinogenic ghost cell tumor (DGCT) is considered as a neoplastic counterpart of the calcifying odo...
INTRODUCTION: Although altered regulation of the Wnt pathway via beta-catenin is a frequent event in...
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and accounts for about 5% ...
# The Author(s) 2010. This article is published with open access at Springerlink.com Abstract In can...
Ankara : Department of Molecular Biology and Genetics and Institute of Engineering and Science of Bi...
β-catenin is involved in cell adhesion through catenin-cadherin complexes and as a transcriptional r...
Background beta-catenin, a 92 kDa protein that binds to the cytoplasmic tail of E-cadherin, has an e...
The molecular events that precede the development of osteosarcoma, the most common primary malignanc...