The hypothesis that hepatocellular proliferative changes give rise to autono-mous, neoplastic lesions in rodents was tested in this study in which hepatopro-liferative lesions induced in rats by feeding an experimental psychoactive drug, cyproximide, were examined at various times during the course of a 24 month study. A total of I 10 male and female rats (Charles River laboratorie
Experiments were designed to determine whether liver cell proliferation induced by direct mitogens i...
Background/aims. Hepatocellular carcinoma is one of the most commonly diagnosed malignant tumors in ...
Different protocols of chemically induced hepatocarcinogenesis were applied to Wisfar rats under ide...
The morphological and cytochemical changes occurring in liver of male Sprague-Dawley rats receiving ...
Abstract: In this comparative review, histomorphological features of common nonneoplastic and neopla...
The morphological and cytochemical changes occurring in liver of male Sprague-Dawley rats receiving ...
Part I - For harmonization of liver diagnostic nomenclature, the establishment of an international n...
Background: Liver preneoplasia development in rats can be mimicked by an initiation-promotion model ...
Hepatocellular carcinoma (HCC) is one of the most life-threatening cancers. The present study was de...
Preclinical toxicity studies have demonstrated that exposure of laboratory animals to liver enzyme i...
Hepatocytic neoplasms (nodules and carcinomas) and islands of cellular alteration which display abno...
Classification of rat hepatocellular proliferative lesions can vary between pathologists as the many...
Our earlier studies have revealed that direct hyperplasia induced by liver mitogens such as lead nit...
Many strains of mice have relatively high background incidences of liver cell tumours which can be r...
A series of experiments was performed to investigate the effect of different types of cell prolifera...
Experiments were designed to determine whether liver cell proliferation induced by direct mitogens i...
Background/aims. Hepatocellular carcinoma is one of the most commonly diagnosed malignant tumors in ...
Different protocols of chemically induced hepatocarcinogenesis were applied to Wisfar rats under ide...
The morphological and cytochemical changes occurring in liver of male Sprague-Dawley rats receiving ...
Abstract: In this comparative review, histomorphological features of common nonneoplastic and neopla...
The morphological and cytochemical changes occurring in liver of male Sprague-Dawley rats receiving ...
Part I - For harmonization of liver diagnostic nomenclature, the establishment of an international n...
Background: Liver preneoplasia development in rats can be mimicked by an initiation-promotion model ...
Hepatocellular carcinoma (HCC) is one of the most life-threatening cancers. The present study was de...
Preclinical toxicity studies have demonstrated that exposure of laboratory animals to liver enzyme i...
Hepatocytic neoplasms (nodules and carcinomas) and islands of cellular alteration which display abno...
Classification of rat hepatocellular proliferative lesions can vary between pathologists as the many...
Our earlier studies have revealed that direct hyperplasia induced by liver mitogens such as lead nit...
Many strains of mice have relatively high background incidences of liver cell tumours which can be r...
A series of experiments was performed to investigate the effect of different types of cell prolifera...
Experiments were designed to determine whether liver cell proliferation induced by direct mitogens i...
Background/aims. Hepatocellular carcinoma is one of the most commonly diagnosed malignant tumors in ...
Different protocols of chemically induced hepatocarcinogenesis were applied to Wisfar rats under ide...