Purpose: The aim of this study was to examine the expression of E-cadherin, β-catenin, Cdx2, MMP7 in gastric cancer and to evaluate the clinical significance of these molecules in tumor recurrence within 2 years of pT2 and N1/N2 gastric cancer. Methods: In 122 patients who underwent radical resection of gastric cancer, we investigated the association between the expression of these molecules and clinicopathologic factors by immunohistochemistry. The included criteria were pT2 and N1 or N2 (6th AJCC TNM). Results: The expression of MMP7 was significantly associated with N stage (N1 vs. N2) (P=0.011). The negative expression of β-catenin was strongly correlated with tumor recurrence within a 2-year period. However, the expression of these mol...
Purpose: Recent investigations have demonstrated that hypermethylation is a frequent mechanism for s...
Gastric cancer is the fifth most common cancer and the third most common cause of cancer death all o...
Purpose: The present paper sought investigate the existence of parameters useful for predicting lymp...
Background and Aim: Decrease in expression of the E-cadherin-catenin complex is an important element...
Background: The molecular pathogenesis of gastric carcinoma is not yet well characterized. The purpo...
Dysfunction of E-cadherin and eaten in has been linked to invasiveness and differentiation of tumors...
BACKGROUND: The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and...
Purpose: E-cadherin and catenins are important epithelial adhesion molecules in normal epithelium. L...
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Purpose: Aberrant expression of proteins involved in epithelial-to-mesenchymal transition have been ...
The prognosis of gastric cancer (GC) is associated with Cdx2 and nuclear PTEN coexpression. This stu...
The E-cadherin-catenin complex plays an important role in the process of cell adhesion. Its dysfunct...
The aim of the study was to analyze the expression of Cdx2 and nuclear PTEN in relation to clinicopa...
PURPOSE: Recent investigations have demonstrated that hypermethylation is a frequent mechanism for s...
OBJECTIVE To observe the expression of PTEN and E-Cadherin in gastric carcinomas (GCs), and to inves...
Purpose: Recent investigations have demonstrated that hypermethylation is a frequent mechanism for s...
Gastric cancer is the fifth most common cancer and the third most common cause of cancer death all o...
Purpose: The present paper sought investigate the existence of parameters useful for predicting lymp...
Background and Aim: Decrease in expression of the E-cadherin-catenin complex is an important element...
Background: The molecular pathogenesis of gastric carcinoma is not yet well characterized. The purpo...
Dysfunction of E-cadherin and eaten in has been linked to invasiveness and differentiation of tumors...
BACKGROUND: The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and...
Purpose: E-cadherin and catenins are important epithelial adhesion molecules in normal epithelium. L...
To access full text version of this article. Please click on the hyperlink "View/Open" at the bottom...
Purpose: Aberrant expression of proteins involved in epithelial-to-mesenchymal transition have been ...
The prognosis of gastric cancer (GC) is associated with Cdx2 and nuclear PTEN coexpression. This stu...
The E-cadherin-catenin complex plays an important role in the process of cell adhesion. Its dysfunct...
The aim of the study was to analyze the expression of Cdx2 and nuclear PTEN in relation to clinicopa...
PURPOSE: Recent investigations have demonstrated that hypermethylation is a frequent mechanism for s...
OBJECTIVE To observe the expression of PTEN and E-Cadherin in gastric carcinomas (GCs), and to inves...
Purpose: Recent investigations have demonstrated that hypermethylation is a frequent mechanism for s...
Gastric cancer is the fifth most common cancer and the third most common cause of cancer death all o...
Purpose: The present paper sought investigate the existence of parameters useful for predicting lymp...