Observational clinical studies link acute kidney injury to chronic kidney disease (CKD) progression. The pathophy-siological mechanisms that underlie this process are cur-rently unknown but recently published papers suggest that tubular epithelial cells and interstitial mesenchymal cells emerge as a single unit, and their integrity alteration as a whole might lead to renal fibrosis and CKD. The present article reviews the biological findings supporting the hypothesis of an altered epithelial/mesenchymal crosstalk in fibrosis development and progression toward CKD
Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving systemic orga...
Acute kidney injury (AKI) is characterized by a rapid deterioration of kidney function, representing...
Abstract Acute kidney injury (AKI) has gained significant attention following patient...
Observational clinical studies link acute kidney injury to chronic kidney disease (CKD) progression....
Observational clinical studies link acute kidney injury to chronic kidney disease (CKD) progression....
The incidence of chronic kidney diseases (CKD) is constantly rising, reaching epidemic proportions i...
Acute kidney injury (AKI) is an increasing health burden with high morbidity and mortality rates wor...
Systemic inflammation is known to target tubular epithelial cells (TECs), leading to acute kidney in...
Acute kidney injury (AKI) is defined as a pathological condition in which the glomerular filtration ...
Chronic kidney disease (CKD) is defined as any condition that causes reduced kidney function over a ...
Background: Acute kidney injury (AKI), even if followed by renal recovery, is a risk factor for the ...
Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here, we re...
Interstitial fibrosis, a histological process common to many kidney diseases, is the precursor state...
Chronic kidney disease (CKD) remains one of the leading causes of death in the developed world, and ...
Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving systemic orga...
Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving systemic orga...
Acute kidney injury (AKI) is characterized by a rapid deterioration of kidney function, representing...
Abstract Acute kidney injury (AKI) has gained significant attention following patient...
Observational clinical studies link acute kidney injury to chronic kidney disease (CKD) progression....
Observational clinical studies link acute kidney injury to chronic kidney disease (CKD) progression....
The incidence of chronic kidney diseases (CKD) is constantly rising, reaching epidemic proportions i...
Acute kidney injury (AKI) is an increasing health burden with high morbidity and mortality rates wor...
Systemic inflammation is known to target tubular epithelial cells (TECs), leading to acute kidney in...
Acute kidney injury (AKI) is defined as a pathological condition in which the glomerular filtration ...
Chronic kidney disease (CKD) is defined as any condition that causes reduced kidney function over a ...
Background: Acute kidney injury (AKI), even if followed by renal recovery, is a risk factor for the ...
Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here, we re...
Interstitial fibrosis, a histological process common to many kidney diseases, is the precursor state...
Chronic kidney disease (CKD) remains one of the leading causes of death in the developed world, and ...
Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving systemic orga...
Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving systemic orga...
Acute kidney injury (AKI) is characterized by a rapid deterioration of kidney function, representing...
Abstract Acute kidney injury (AKI) has gained significant attention following patient...