Add to ORKGAbstract-The ffect of aging on the ability of macrophages to produce ndogenous pyrogen/interleukin-1 (EP/IL-I) was tested in 13 young adult (2-3 mo) and 13 aged (24-26 mo) Fischer rats using a febrile response assay. Peritoneal macrophages from aged rats produced EP/IL-1 as well as young adult rats. Decreased production of EP/IL-1 does not appear to explain the diminished febrile response seen in the elderly. Key Words: endogenous pyrogen, interleukin-1, febrile response, maerophages, fever in aged rat
Background. A blunted or absent fever response to infection may occur in elderly people. Fever is me...
Aging is associated with a deterioration of the acute phase response to inflammatory challenges. How...
<p>All data were determined under fed conditions. Values (pg/ml) are mean ± SEM for the number (<i>n...
The effect of aging on the ability of macrophages to produce endogenous pyrogen/interleukin-1 (EP/IL...
ated with a blunted or absent fever response to naturally occurring infections or to the peripheral ...
There is considerable controversy about the molecular mechanisms responsible for the variations in i...
Altered functions of macrophages with aging contribute to impairment of both innate and adaptive imm...
Aged and protein‐malnourished hosta have diminished febrile responses and increased morbidity and mo...
We assessed the effect of protein deprivation on the ability of peritoneal macrophages from Fischer ...
In humans, usual aging, differently from successful aging, is associated with deregulation of proinf...
Sleep is altered in response to infection and immune challenge in humans and non-human animals. Alth...
The ability of macrophages to secrete cytokines is important in host responses to infections inflamm...
The ability of macrophages to secrete cytokines is important in host responses to infections inflamm...
The phenotype and function of tissue macrophages substantially depend on the cellular milieu and bio...
Abstract: Aged humans and rodents are suscepti-ble to infection with Streptococcus pneumoniae bacter...
Background. A blunted or absent fever response to infection may occur in elderly people. Fever is me...
Aging is associated with a deterioration of the acute phase response to inflammatory challenges. How...
<p>All data were determined under fed conditions. Values (pg/ml) are mean ± SEM for the number (<i>n...
The effect of aging on the ability of macrophages to produce endogenous pyrogen/interleukin-1 (EP/IL...
ated with a blunted or absent fever response to naturally occurring infections or to the peripheral ...
There is considerable controversy about the molecular mechanisms responsible for the variations in i...
Altered functions of macrophages with aging contribute to impairment of both innate and adaptive imm...
Aged and protein‐malnourished hosta have diminished febrile responses and increased morbidity and mo...
We assessed the effect of protein deprivation on the ability of peritoneal macrophages from Fischer ...
In humans, usual aging, differently from successful aging, is associated with deregulation of proinf...
Sleep is altered in response to infection and immune challenge in humans and non-human animals. Alth...
The ability of macrophages to secrete cytokines is important in host responses to infections inflamm...
The ability of macrophages to secrete cytokines is important in host responses to infections inflamm...
The phenotype and function of tissue macrophages substantially depend on the cellular milieu and bio...
Abstract: Aged humans and rodents are suscepti-ble to infection with Streptococcus pneumoniae bacter...
Background. A blunted or absent fever response to infection may occur in elderly people. Fever is me...
Aging is associated with a deterioration of the acute phase response to inflammatory challenges. How...
<p>All data were determined under fed conditions. Values (pg/ml) are mean ± SEM for the number (<i>n...