Dysfunction of the serotonergic system is implicated in the etiology of many psychiatric disorders, including major depres-sion. Major vulnerability genes for mood disorders are also related to the serotonergic system: one of these genes encodes for the serotonin transporter (SERT), which represent a major target for the action of antidepressant drugs. We have demon-strated recently that SERT knockout (KO) rats, generated by N-ethyl-N-nitrosourea-induced mutagenesis, show reduced expression of the neurotrophin brain-derived neurotrophic fac-tor (BDNF) in the hippocampus and prefrontal cortex, suggest-ing that depression vulnerability can be associated with im-paired neuronal plasticity. In the present study, we demonstrate that chronic trea...
It is well established that alterations of the serotoninergic system may contribute to the pathophys...
Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is pr...
Growing evidence supports the involvement of brain-derived neurotrophic factor (BDNF) in mood disord...
Dysfunction of the serotonergic system is implicated in the etiology of many psychiatric disorders, ...
here is growing evidence that brain-derived neurotrophic factor ( BDNF) can be relevant to mood diso...
Abstract Dysfunction of the serotonergic system is implicated in the etiology of many psychiatric di...
In order to identify the molecular mechanisms that may contribute to the enhanced susceptibility to ...
Compelling evidence suggests that mood disorders are characterized by reduced neuronal plasticity th...
During the last few years several studies have highlighted the possibility that major depression can...
Item does not contain fulltextAlterations of the serotonergic system are involved in the pathophysio...
During the last few years several studies have highlighted the possibility that major depression can...
Contains fulltext : 89453.pdf (Publisher’s version ) (Closed access)In order to id...
Recent studies indicate that brain-derived neurotrophic factor (BDNF) may be implicated in the clini...
Monoamine reuptake inhibitors increase brain-derived neurotrophic factor (BDNF) activity, and this g...
Background: Recent rodent studies reported that antidepressant treatments affect the expression of b...
It is well established that alterations of the serotoninergic system may contribute to the pathophys...
Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is pr...
Growing evidence supports the involvement of brain-derived neurotrophic factor (BDNF) in mood disord...
Dysfunction of the serotonergic system is implicated in the etiology of many psychiatric disorders, ...
here is growing evidence that brain-derived neurotrophic factor ( BDNF) can be relevant to mood diso...
Abstract Dysfunction of the serotonergic system is implicated in the etiology of many psychiatric di...
In order to identify the molecular mechanisms that may contribute to the enhanced susceptibility to ...
Compelling evidence suggests that mood disorders are characterized by reduced neuronal plasticity th...
During the last few years several studies have highlighted the possibility that major depression can...
Item does not contain fulltextAlterations of the serotonergic system are involved in the pathophysio...
During the last few years several studies have highlighted the possibility that major depression can...
Contains fulltext : 89453.pdf (Publisher’s version ) (Closed access)In order to id...
Recent studies indicate that brain-derived neurotrophic factor (BDNF) may be implicated in the clini...
Monoamine reuptake inhibitors increase brain-derived neurotrophic factor (BDNF) activity, and this g...
Background: Recent rodent studies reported that antidepressant treatments affect the expression of b...
It is well established that alterations of the serotoninergic system may contribute to the pathophys...
Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is pr...
Growing evidence supports the involvement of brain-derived neurotrophic factor (BDNF) in mood disord...