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Mice lacking Nf1 in

Weixi Wang
Jeffry S. Nyman
Koichiro Ono
David A. Stevenson
Xiangli Yang
Florent Elefteriou

Publication date

January 2011

Abstract

osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type

Extracted data

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Paige Snider
Er G. Robling
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Kolanczyk, M.
Kossler, N.
Kühnisch, J.
Lavitas, L.
Stricker, S.
Wilkening, U.
Manjubala, I.
Fratzl, P.
Spörle, R.
Herrmann, B.
Parada, L.
Kornak, U.
Mundlos, S.

February 2007

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Marie Gdalevitch
Nigel Turner
Gregory J Cooney
Mateusz Kolanczyk
Kathryn N North
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January 2013

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Sullivan, Kate
El-hoss, Jad
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Deo, Nikita
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Seto, Jane T.C.
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Cooney, Gregory J.
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North, Kathryn N.
Little, David G.
Schindeler, Aaron

March 2014

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Multiscale, Converging Defects of Macro-Porosity, Microstructure and Matrix Mineralization Impact Long Bone Fragility in NF1

Jirko Kühnisch (108599)
Jong Seto (126700)
Claudia Lange (233575)
Susanne Schrof (512084)
Sabine Stumpp (512085)
Karolina Kobus (512086)
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Nadine Kossler (456768)
Peter Varga (512088)
Monika Osswald (512089)
Denise Emmerich (512090)
Sigrid Tinschert (483418)
Falk Thielemann (512091)
Georg Duda (283456)
Wenke Seifert (512092)
Thaqif el Khassawna (5657647)
David A. Stevenson (512093)
Florent Elefteriou (150791)
Uwe Kornak (512094)
Kay Raum (372828)
Peter Fratzl (126726)
Stefan Mundlos (42602)
Mateusz Kolanczyk (512095)

January 2014

<div><p>Bone fragility due to osteopenia, osteoporosis or debilitating focal skeletal dysplasias is ...

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Steven D Rhodes
Wei Zhang
Dalong Yang
Hao Yang
Shi Chen
Xiaohua Wu
Xiaohong Li
Xianlin Yang
Khalid S Mohammad
Theresa A Guise
Amanda L Bergner
David A Stevenson
Feng-Chun Yang

Despite the high prevalence and significant morbidity of spinal anomalies in neurofibromatosis type ...

Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1

Kühnisch, J.
Seto, J.
Lange, C.
Schrof, S.
Stumpp, S.
Kobus, K.
Grohmann, J.
Kossler, N.
Varga, P.
Oßwald, M.
Emmerich, D.
Tinschert, S.
Thielemann, F.
Duda, G.
Seifert, W.
El Khassawna, T.
Stevenson, D.
Elefteriou, F.
Kornak, U.
Raum, K.
Fratzl, P.
Mundlos, S.
Kolanczyk, M.

January 2014

Bone fragility due to osteopenia, osteoporosis or debilitating focal skeletal dysplasias is a freque...

Multiscale, Converging Defects of Macro-Porosity, Microstructure and Matrix Mineralization Impact Long Bone Fragility in NF1

Kühnisch, Jirko
Seto, Jong
Kolanczyk, Mateusz

January 2014

Bone fragility due to osteopenia, osteoporosis or debilitating focal skeletal dysplasias is a freque...

Mouse models of tumor development in neurofibromatosis type 1.

Cichowski, K
Shih, T S
Schmitt, E
Santiago, S
Reilly, K
McLaughlin, M E
Bronson, R T
Jacks, T

January 1999

Neurofibromatosis type 1 (NF1) is a prevalent familial cancer syndrome resulting from germ line muta...

Nf1 haploinsufficiency alters myeloid lineage commitment and function, leading to deranged skeletal homeostasis

Rhodes, Steven D.
Yang, Hao
Dong, Ruizhi
Menon, Keshav
He, Yongzheng
Li, Zhaomin
Chen, Shi
Staser, Karl W.
Jiang, Li

October 2015

Although nullizygous loss of NF1 leads to myeloid malignancies, haploinsufficient loss of NF1 (Nf1) ...

Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse models

Kühnisch, J.
Seto, J.
Lange, C.
Stumpp, S.
Kobus, K.
Grohmann, J.
Elefteriou, F.
Fratzl, P.
Mundlos, S.
Kolanczyk, M.

September 2014

Neurofibromin has been identified as a critical regulator of osteoblast differentiation. Osteoblast ...

Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1

De La Croix Ndong, Jean
Makowski, Alexander J.
Uppuganti, Sasidhar
Vignaux, Guillaume
Ono, Koichiro
Perrien, Daniel S.
Joubert, Simon
Baglio, Serena R.
Granchi, Donatella
Stevenson, David A.
Rios, Jonathan J.
Nyman, Jeffry S.
Elefteriou, Florent

January 2014

Individuals with neurofibromatosis type-1 (NF1) can manifest focal skeletal dysplasias that remain e...