Korea

Peripheral neuropathy is somewhat common in hypothyroidism. But, demyelinating peripheral neuropathy in Hashimoto’s thyroiditis is extremely rare. The pathophysiology of demyelinating peripheral neuropathy associated with Hashimoto’s thy-roiditis is unclear and complex and various mechanisms including the cell mediated and antibody mediated responses may be operative. We report a 68-year-old woman who presented with paresthesia and gait disturbance. She was diag-nosed with hypothyroidism 7 years prior and has been on thyroid hormone. Serum antithyroglobulin antibody was signi-ficantly elevated. Nerve conduction studies revealed sensory-motor demyelinating polyneuropathy with prolonged distal latencies and reduced conduction velocities. She was under the suspicion of the lymphoma of thyroid. Surgery was per-formed which turned up to be Hashimoto’s thyroiditis. With the impression of rare demyelinating peripheral neuropathy associated with Hashimoto’s thyroiditis after other causes were excluded, she was treated with steroid which amelio