Intravenous treatment of systemic infections in 20 patients uri+h pofnvifin crtsliiimwith cefoxitin sodiu

Intravenous cefoxitin sodium was administered to 20 patients with moderate to severe infections; 10 patients had undergone surgery. Thirty-eight strains of bacteria, were isolated. Among 8 anaerobes isolated initially, 7 were sensitive to cefoxitin, 5 sensitive to cephalothin; among 17 Gram-negative rods, 15 were sensitive to cefoxitin, 12 to cephalothin. Six bacterial strains resistant to cephalothin proved sensitive to cefoxitin, whereas only 2 strains were resistant to cefoxitin but sensitive to cephalothin. All 20 patients were cured; there were no adverse effects, nor any local reactions at injection sites