Add to ORKGHypothalamic nesfatin-1, derived from the nucleobindin2 (NUCB2) precursor, inhibits nocturnal food intake and body weight gain in rats. Nesfatin-1 is able to cross the blood-brain barrier, suggesting a peripheral source of nesfatin-1. Many centrally acting food intake regulatory neu-ropeptides are also produced in the periphery, especially in the gastrointestinal tract. Therefore, we investigated thegeneexpressionofNUCB2anddistributionof nesfatin-1-immunoreactive cells in the stomach.MicroarraymRNAexpressionprofiles in purified small endocrine cells of the gastric mucosa substantiated by quantitative RT-PCR showed significantly higher NUCB2 mRNA expres-sion comparedwith brain and heart.Western blot confirmed the expression of NUCB2 protein ...
Nesfatin-1 is secreted, meal-responsive anorexigenic peptide encoded in the precursor nucleobindin-2...
Whole-body energy homeostasis is regulated by the endocrine system via a spectrum of hormones. Nucle...
Nesfatin-1, product of the precursor NEFA/nucleobindin2 (NUCB2), was initially identified as anorect...
<div><p>Nesfatin-1 is secreted, meal-responsive anorexigenic peptide encoded in the precursor nucleo...
Hunger and satiety are regulated in a complex fashion by a few food intake stimulatory (orexigenic) ...
Originally identified in the hypothalamus as a satiety factor, recent studies provide evidence that ...
Nesfatin-1 was discovered in 2006 and introduced as a potential novel anorexigenic modulator of food...
Nesfatin-1 is a novel anorexigenic regulatory peptide. The peptide is the N-terminal part of nucleob...
Nesfatin-1 is a novel anorexigenic regulatory peptide. The peptide is the N-terminal part of nucleob...
Nucleobindins are a class of secreted, multi-domain Ca2+ binding proteins that interact with nucleic...
<div><p>Nucleobindin-1 has high sequence similarity to nucleobindin-2, which encodes the anorectic a...
Whole body energy homeostasis is regulated by the endocrine system. Nesfatin-1 is a newly identified...
Whole body energy homeostasis is regulated by the endocrine system. Nesfatin-1 is a newly identified...
Whole-body energy homeostasis is regulated by the endocrine system via a spectrum of hormones. Nucle...
Whole-body energy homeostasis is regulated by the endocrine system via a spectrum of hormones. Nucle...
Nesfatin-1 is secreted, meal-responsive anorexigenic peptide encoded in the precursor nucleobindin-2...
Whole-body energy homeostasis is regulated by the endocrine system via a spectrum of hormones. Nucle...
Nesfatin-1, product of the precursor NEFA/nucleobindin2 (NUCB2), was initially identified as anorect...
<div><p>Nesfatin-1 is secreted, meal-responsive anorexigenic peptide encoded in the precursor nucleo...
Hunger and satiety are regulated in a complex fashion by a few food intake stimulatory (orexigenic) ...
Originally identified in the hypothalamus as a satiety factor, recent studies provide evidence that ...
Nesfatin-1 was discovered in 2006 and introduced as a potential novel anorexigenic modulator of food...
Nesfatin-1 is a novel anorexigenic regulatory peptide. The peptide is the N-terminal part of nucleob...
Nesfatin-1 is a novel anorexigenic regulatory peptide. The peptide is the N-terminal part of nucleob...
Nucleobindins are a class of secreted, multi-domain Ca2+ binding proteins that interact with nucleic...
<div><p>Nucleobindin-1 has high sequence similarity to nucleobindin-2, which encodes the anorectic a...
Whole body energy homeostasis is regulated by the endocrine system. Nesfatin-1 is a newly identified...
Whole body energy homeostasis is regulated by the endocrine system. Nesfatin-1 is a newly identified...
Whole-body energy homeostasis is regulated by the endocrine system via a spectrum of hormones. Nucle...
Whole-body energy homeostasis is regulated by the endocrine system via a spectrum of hormones. Nucle...
Nesfatin-1 is secreted, meal-responsive anorexigenic peptide encoded in the precursor nucleobindin-2...
Whole-body energy homeostasis is regulated by the endocrine system via a spectrum of hormones. Nucle...
Nesfatin-1, product of the precursor NEFA/nucleobindin2 (NUCB2), was initially identified as anorect...