Inhibition
Publication date
September 2016
DOIAbstract
of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastom
of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastom
Activation of Mechanistic target of rapamycin (mTOR) signaling plays a crucial role in tumorigenesis...
Mechanistic target of rapamycin (mTOR), which functions via two multiprotein complexes termed mTORC1...
Initiation is the rate-limiting phase of protein synthesis, controlled by signaling pathways regulat...
A variety of mechanisms confer hypersensitivity of tumor cells to the macrolide rapamycin, the proto...
Protein synthesis is important for maintaining cellular homeostasis under various stress responses. ...
BackgroundClinical trials of therapies directed against nodes of the signaling axis of phosphatidyli...
Increasing evidence suggests that an inflammatory microenvironment promotes invasion by glioblastoma...
Cell size within animal tissues is highly uniform. Previous data has shown that the p38 pathway pla...
Activation of PI3K/Akt/mTOR (mechanistic target of rapamycin) signaling cascade has been shown in tu...
Summary: p38 signaling is broadly involved in controlling inflammation and stress-induced cell death...
Aberrant signaling of mechanistic target of rapamycin (mTOR aka mammalian target of rapamycin) is sh...
Mutual stabilization between TRIM9 short isoform and MKK6 potentiates p38 signaling to synergistical...
<p>Multiple signaling pathways control protein synthesis by modulating translation initiation factor...
textabstractBackground: Glioblastoma is the most malignant tumor of the central nervous system and s...
Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals ...
Activation of Mechanistic target of rapamycin (mTOR) signaling plays a crucial role in tumorigenesis...
Mechanistic target of rapamycin (mTOR), which functions via two multiprotein complexes termed mTORC1...
Initiation is the rate-limiting phase of protein synthesis, controlled by signaling pathways regulat...
A variety of mechanisms confer hypersensitivity of tumor cells to the macrolide rapamycin, the proto...
Protein synthesis is important for maintaining cellular homeostasis under various stress responses. ...
BackgroundClinical trials of therapies directed against nodes of the signaling axis of phosphatidyli...
Increasing evidence suggests that an inflammatory microenvironment promotes invasion by glioblastoma...
Cell size within animal tissues is highly uniform. Previous data has shown that the p38 pathway pla...
Activation of PI3K/Akt/mTOR (mechanistic target of rapamycin) signaling cascade has been shown in tu...
Summary: p38 signaling is broadly involved in controlling inflammation and stress-induced cell death...
Aberrant signaling of mechanistic target of rapamycin (mTOR aka mammalian target of rapamycin) is sh...
Mutual stabilization between TRIM9 short isoform and MKK6 potentiates p38 signaling to synergistical...
<p>Multiple signaling pathways control protein synthesis by modulating translation initiation factor...
textabstractBackground: Glioblastoma is the most malignant tumor of the central nervous system and s...
Mammalian target of rapamycin (mTOR) is a conserved serine/threonine kinase that integrates signals ...
Activation of Mechanistic target of rapamycin (mTOR) signaling plays a crucial role in tumorigenesis...
Mechanistic target of rapamycin (mTOR), which functions via two multiprotein complexes termed mTORC1...
Initiation is the rate-limiting phase of protein synthesis, controlled by signaling pathways regulat...
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