Incidence of Tuberculosis in the United States among

Background: The resurgence of tuberculosis in the United States is largely linked to the human immunodefi-ciency virus (HIV) epidemic. Despite this link, the epidemi-ology of tuberculosis and preventive strategies in patients infected with HIV are not completely understood. Objectives: To determine the incidence and predictors of tuberculosis in HIV-infected persons. Design: Prospective, multicenter cohort study. Setting: Community-based cohort of persons with and without HIV infection at centers in the eastern, midwest-em, and western United States. Participants: 1130 HIV-seropositive patients without AIDS who were followed for a median of 53 months (814 homosexual men, 261 injection drug users, and 55 women who had acquired HIV through heterosexual contact)