Role of DNA methylation in the tissue-specific expression e

an n an tzer eu, f.uni CYP17A1 gene and have therefore no P450c17 enzyme for tical Y1 cells which normally do not express CYP17, et al. 1991, Fan et al. 1992). P450c17 is the qualitative human adrenal zona glomerulosa (Miller et al. 1997). In the Miller 1986, Voutilainen et al. 1986, Di Blasio et al. 1987, Because the CYP17A1 gene is not expressed in rodent In addition, the CYP17A1 gene is expressed in some non-5-position of cytosine in CpG islands within DNA strand