Add to ORKGBackground: Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism which is involved in DNA methylation, repair, and synthesis. Objective: We investigated if the MTHFR C677T polymorphism modulates the risk of developing breast cancer in Moroccan women. Methods: Genotyping was performed by PCR-RFLP method on a sample of 96 patients with breast cancer and 117 controls. Results: A positive correlation was found between the MTHFR C677T polymorphism and progesterone receptors expression (p = 0.04). According to menopausal status, the heterozygous CT (OR = 2.29 and P = 0.03) was statistically significant in pre-menopausal women. There was a significant association between C677T polymorphism and breast cancer risk in...
BACKGROUND: The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that othe...
Objective: In our study, the relationship between C677T and tandem repeat sequence polymorphisms in ...
The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of d...
OBJECTIVE:Methylenetetrahydrofolate reductase (MTHFR), a polymorphic enzyme involved in folate metab...
Background: Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism wh...
Background: Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism wh...
The methylenetetrahydrofolate reductase (MTHFR) gene has been proposed as a candidate gene for breas...
Item does not contain fulltextBACKGROUND: The variable penetrance of breast cancer in BRCA1/2 mutati...
BACKGROUND: A growing body of evidence suggests that variations in the levels of folate may contribu...
Background: Polymorphisms in methylenetetrahydrofolate reductase (MTHFR), such as MTHFR C677T and A1...
The methylenetetrahydrofolate reductase (MTHFR) gene plays an important role in the steps involved i...
BACKGROUND: Folate is involved in DNA synthesis and methylation and may thereby influence carcinogen...
Purpose: Gene silencing by hypermethylation plays an important role in proximal colon carcinogenesis...
Background: The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that othe...
BACKGROUND: The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that othe...
BACKGROUND: The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that othe...
Objective: In our study, the relationship between C677T and tandem repeat sequence polymorphisms in ...
The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of d...
OBJECTIVE:Methylenetetrahydrofolate reductase (MTHFR), a polymorphic enzyme involved in folate metab...
Background: Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism wh...
Background: Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism wh...
The methylenetetrahydrofolate reductase (MTHFR) gene has been proposed as a candidate gene for breas...
Item does not contain fulltextBACKGROUND: The variable penetrance of breast cancer in BRCA1/2 mutati...
BACKGROUND: A growing body of evidence suggests that variations in the levels of folate may contribu...
Background: Polymorphisms in methylenetetrahydrofolate reductase (MTHFR), such as MTHFR C677T and A1...
The methylenetetrahydrofolate reductase (MTHFR) gene plays an important role in the steps involved i...
BACKGROUND: Folate is involved in DNA synthesis and methylation and may thereby influence carcinogen...
Purpose: Gene silencing by hypermethylation plays an important role in proximal colon carcinogenesis...
Background: The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that othe...
BACKGROUND: The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that othe...
BACKGROUND: The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that othe...
Objective: In our study, the relationship between C677T and tandem repeat sequence polymorphisms in ...
The methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been linked to the risk of d...