Randomized Controlled Trial DOI: 10.2337/dc14-1728 OBJECTIVE

Depression is common in diabetes and linked to adverse health outcomes. This study evaluated the efficacy of a guided web-based intervention in reducing de-pression in adults with type 1 and type 2 diabetes. RESEARCH DESIGN AND METHODS A total of 260 participants with diabetes and elevated depressive symptoms (Center for Epidemiological Studies Depression Scale [CES-D ‡23]) were randomly assigned to the GET.ONMood Enhancer Diabetes (a guided self-help intervention, n = 130) or a brief online unguided psychoeducation program for depression (n = 130). The primary outcome was depressive symptoms severity (CES-D). The sec-ondary outcomes included diabetes-specific emotional distress (Problem Areas in Diabetes [PAID] scale) and participant satisfaction (adaption CSQ-8). Data were collected at baseline and 2 months after randomization. To identify differences in outcome between the groups, we used analyses of covariance with the baseline CES-D score as covariate on both intent-to-treat (ITT) and per-protocol (PP) basis. RESULT