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Sponsorships or competing interests that may be relevant to content are dis-closed at the end of this article. Objective. The optimal type of neck dissection in head and neck squamous cell carcinoma (SCC) with clinical cervical metastases has not been determined. The following study was performed to determine the rate of regional control with selective neck dissection (SND) in these patients. Study Design. Case series with planned data collection. Setting. Single institution, cancer center. Methods and Subjects. Patients with cervical lymph node metastases from mucosal cancers of the head and neck who were treated with SND from 2000 to 2010 were selected. Demographics, tumor characteristics, extent of neck dissec-tion, adjuvant treatments, locoregional control, and surviva