THYROID TUMOR OF THE HUMERUS WITHOUT DEMONSTRABLE GOITER REPORT OF A CASE WITH BIOLOGICAL ASSAY OF THE TUMOR

So-called benign metastasizing goiter has been known since Cohnheim (lescribed the first case in 1876. In 1926 Simpson thoroughly reviewed seventy-seven reported cases and added three of his own. In this study he mentioned two cases recorded by Zapelloni, wherein there were no signs of goiter or of thyroid cancer. In 1927 Prof. Alessandri of Rome mentioned several similar cases reported in the literature and added two of his own, in which no primary lesion was discovered in the thyroid gland. One of his cases was of particular interest to the authors, since in many details the findings were similar to those in their own case. Alessandri’s patient was a laborer, fifty-one years old, who fell on his right shoulder, sustaining a trauma that resulted in a certain amount of limitation of motion. Three years later, he again fell on the same shoulder, and an enlargement of the bone followed. Physical and roentgenographic examinations revealed an expansile tumor of the head of the humerus. The upper end of the humerus was resected. The tumor recurre