Add to ORKGOver the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug discovery. In this study, we explore the suitability of zebrafish larvae to rapidly evaluate the anti-inflammatory activity of natural products (NPs) and medicinal plants used in traditional medicine for the treatment of inflammatory disorders. First, we optimized a zebrafish assay for leukocyte migration. Inflammation was induced in four days post-fertilization (dpf) zebrafish larvae by tail transection and co-incubation with bacterial lipopolysaccharides (LPS), resulting in a robust recruitment of leukocytes to the zone of injury. Migrating zebrafish leukocytes were detected in situ by myeloperoxidase (MPO) staining, and anti-inflammatory ac...
<p><b>A</b> to <b>C</b>, zebrafish larvae are 4 dpf (days post-fertilization) with anterior to the l...
<p>Anti-inflammatory activity was determined in an acute inflammation assay based on tail transectio...
Zebrafish larvae are particularly amenable to whole animal small molecule screens1,2 due to their sm...
Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug d...
Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug d...
Lipopolysaccharide (LPS), an endotoxin molecule, has been used to induce inflammatory responses. In ...
This study aims to demonstrate the applicability and importance of zebrafish (Danio rerio) model to ...
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014The principal aim of this work...
Background: Studies on innate immunity have benefited from the introduction of zebrafish as a model ...
Context: Inflammatory disease is a big threat to human health. Leukocyte chemotactic migration is re...
Abstract Neutrophilic inflammation in the lung protects against infectious disease, and usually reso...
Tissue injury and infection trigger innate immune responses. However, dysregulation may result in ch...
Background: Studies on innate immunity have benefited from the introduction of zebrafish as a model ...
Tissue injury and infection trigger innate immune responses. However, dysregulation may result in ch...
Cell migration is fundamental to the inflammatory response, but uncontrolled cell migration and exce...
<p><b>A</b> to <b>C</b>, zebrafish larvae are 4 dpf (days post-fertilization) with anterior to the l...
<p>Anti-inflammatory activity was determined in an acute inflammation assay based on tail transectio...
Zebrafish larvae are particularly amenable to whole animal small molecule screens1,2 due to their sm...
Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug d...
Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug d...
Lipopolysaccharide (LPS), an endotoxin molecule, has been used to induce inflammatory responses. In ...
This study aims to demonstrate the applicability and importance of zebrafish (Danio rerio) model to ...
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014The principal aim of this work...
Background: Studies on innate immunity have benefited from the introduction of zebrafish as a model ...
Context: Inflammatory disease is a big threat to human health. Leukocyte chemotactic migration is re...
Abstract Neutrophilic inflammation in the lung protects against infectious disease, and usually reso...
Tissue injury and infection trigger innate immune responses. However, dysregulation may result in ch...
Background: Studies on innate immunity have benefited from the introduction of zebrafish as a model ...
Tissue injury and infection trigger innate immune responses. However, dysregulation may result in ch...
Cell migration is fundamental to the inflammatory response, but uncontrolled cell migration and exce...
<p><b>A</b> to <b>C</b>, zebrafish larvae are 4 dpf (days post-fertilization) with anterior to the l...
<p>Anti-inflammatory activity was determined in an acute inflammation assay based on tail transectio...
Zebrafish larvae are particularly amenable to whole animal small molecule screens1,2 due to their sm...