Epigenetics had changed many beliefs about biological mechanisms and processes from molecular to cellular. Strong epigenetic components have been found involved in the progression of many diseases. Epigenetics also serves as a mechanism of disease action and progression for most of the psychiatric disorders. Researchers are now having a kind of hope to reverse these epigenetic mechanisms as several studies have found the epigenetic progression of disease to be reversible. Being reversible it is assumed research should be done on drug development which can act as potential therapeutics for disease involving epigenetic progression. In this article we presume that the practice of epigenetic drug development could bear a potential risk. Conside...
Epigenetic abnormalities, such as aberrant methylation of CpG islands, are inherited over cell divis...
Epigenetic deregulation is a hallmark of cancer, and there has been increasing interest in therapeut...
mous opportunities to gain a greater understanding of the genetic intricacies underlying biological ...
The epigenome comprises a range of covalent modifications of DNA and histone proteins that establish...
Individuals with neuropsychiatric diseases have epigenetic programming disturbances, both in the bra...
Epigenetics, heritable changes in gene expression that do not involve changes in DNA sequence, is kn...
Abstract: The number of children with mild neurodevelopmental disorders, such as autism, has been re...
The flexibility of the epigenome has generated an enticing argument to explore its reversion through...
Copyright © 2013 E. Hatzimichael and T. Crook.This is an open access article distributed under theCr...
The epigenetic modifications can change the state of selective part in the DNA by different enzymes ...
A key feature of cancer is dysregulation of gene activity and gene expression, which is driven by a ...
Epigenetic changes such as promoter specific DNA hypermethylation and histone deacetylation cause tu...
""Epigenetic inactivation of pivotal genes involved in correct cell growth is a hallmark of human pa...
Making quick promises of major biomedical breakthroughs based on exciting discoveries at the bench i...
Epigenetics is rising to prominence in biology as a mechanism by which environmental factors have in...
Epigenetic abnormalities, such as aberrant methylation of CpG islands, are inherited over cell divis...
Epigenetic deregulation is a hallmark of cancer, and there has been increasing interest in therapeut...
mous opportunities to gain a greater understanding of the genetic intricacies underlying biological ...
The epigenome comprises a range of covalent modifications of DNA and histone proteins that establish...
Individuals with neuropsychiatric diseases have epigenetic programming disturbances, both in the bra...
Epigenetics, heritable changes in gene expression that do not involve changes in DNA sequence, is kn...
Abstract: The number of children with mild neurodevelopmental disorders, such as autism, has been re...
The flexibility of the epigenome has generated an enticing argument to explore its reversion through...
Copyright © 2013 E. Hatzimichael and T. Crook.This is an open access article distributed under theCr...
The epigenetic modifications can change the state of selective part in the DNA by different enzymes ...
A key feature of cancer is dysregulation of gene activity and gene expression, which is driven by a ...
Epigenetic changes such as promoter specific DNA hypermethylation and histone deacetylation cause tu...
""Epigenetic inactivation of pivotal genes involved in correct cell growth is a hallmark of human pa...
Making quick promises of major biomedical breakthroughs based on exciting discoveries at the bench i...
Epigenetics is rising to prominence in biology as a mechanism by which environmental factors have in...
Epigenetic abnormalities, such as aberrant methylation of CpG islands, are inherited over cell divis...
Epigenetic deregulation is a hallmark of cancer, and there has been increasing interest in therapeut...
mous opportunities to gain a greater understanding of the genetic intricacies underlying biological ...