RELATION OF THYROID AND PARATHYROID GLANDS TO CAL- CIUM AND PHOSPHORUS METABOLISM. STUDY OF A CASE WITH COEXISTENT HYPOPARATHYROIDISM AND

In a series of investigations on the relation of the thyroid to calcium and phosphorus metabolism Aub and his coworkers (1) have demonstrated that increased thyroid activity is associated with an increased excretion of calcium and phosphorus. In exophthalmic goiter there is an increased out-put of calcium not only in the urine but in the feces. In normal individuals who are fed thy-roid there is a similar increase in calcium and phosphorus excretion, and in myxedema there is a diminished excretion which rises toward normal following thyroid therapy. This increase in nega-tive calcium and phosphorus balance is dissimilar to that produced by overactivity of the parathy-roid glands. In hyperparathyroidism the feca