An Improved Procedure for the Synthesis of 1,5-Benzothiazepines Using Ceric Ammonium Nitrate (CAN)

ABSTRACT. A mild and efficient procedure for the synthesis of various 1,5-benzothiazepines were developed. This method provides an easy access for preparation of 1,5-benzothiazepine derivatives in the presence of 10 mol % catalyst of CAN under ultrasonic irradiation. This method provided clean conversion, mild reaction condition, no use of toxic solvent and shorter reaction time compared to other reported method