Multifocal Visual Evoked Potential mfVEP

Commentary Although the multifocal visual evoked potential (mfVEP) was introduced in 1994 by Baseler, Sutter and colleagues [1], its development has lagged behind the multifocal electroretinogram (mfERG). The large inter subject variability in mfVEP responses has discouraged its use. There are two main sources of inter-subject variability. First, the position of the calcarine fissure relative to the external landmarks varies among individuals [2]. Second, individuals differ in the way the cortex is folded and how the primary visual area is positioned within these folds [3,4]. If inter-subject variability is due to cranio-occipital variations, then the mfVEP responses from the two eyes should be identical. The reason for this is purely anatomical; any point in the visual field projects to the nasal retina of one eye and the temporal retina of th