Complete Genome Sequence of Mycobacterium massiliense

Mycobacteriummassiliense is a rapidly growing bacteriumassociatedwith opportunistic infections. The genomeof a representative isolate (strainGO06) recovered fromwound samples frompatientswhounderwent arthroscopic or laparoscopic surgerywas se-quenced. To the best of our knowledge, this is the first announcement of the complete genome sequence of anM.massiliense strain. Rapidly growing mycobacteria (RGM) have important impli-cations in human diseases, as they are frequently associated with infections among immunocompromised patients, as well as wound, skin, and soft tissue infections (9). In addition, these bac-teria are naturally resistant to several classes of antibiotics, partic-ularly antituberculosis drugs. Mycobacterium abscessus is the most important pathogen among RGM; however, in 2004, Adékambi et al. (1) assigned a novel species name to a closely related isolate, Mycobacteriummassiliense.M.massiliensehas since been increasingly reported as causing soft tissue infection outbreaks. In Brazil, our group and others recently reported a major outbreak, with the char-acterization of some aspects of antibiotic resistance, as well as disin-fectant resistance, that may have also contributed to the difficulty i