Add to ORKGPutative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenoma
Objective Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregul...
OBJECTIVE: Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregu...
The intestinal epithelium is a specialized simple epithelium that lines the gut and performs primary...
In order to identify new genes with differential expression in early intestinal tumours, we performe...
In order to identify new genes with differential expression in early intestinal tumours, we performe...
The Apc(Min/+) mouse has emerged as a powerful model of human intestinal tumour predisposition. As s...
BACKGROUND & AIMS: In colorectal cancer, activating mutations in the Wnt pathway transform epithelia...
BACKGROUND: Cancer results from the accumulation of mutations leading to the acquisition of cancer p...
Abstract: Background: Cancer results from the accumulation of mutations leading to the acquisition o...
In colorectal tumours, Wnt pathway genetics continues to be dominated by mutations in the adenomatou...
APC biallelic loss-of-function mutations are the most prevalent genetic changes in colorectal tumors...
Adenomatous polyposis coli (APC) mutations are found in most colorectal tumours. These mutations are...
Germline mutations in the adenomatous polyposis coli (APC) gene are responsible for familial adenoma...
Canonical wnt signaling is important in embryonic development and tumorigenesis of various tissues i...
Around 70 % of sporadic colorectal tumours show bi-allelic inactivation of the APC gene (Adenomatous...
Objective Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregul...
OBJECTIVE: Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregu...
The intestinal epithelium is a specialized simple epithelium that lines the gut and performs primary...
In order to identify new genes with differential expression in early intestinal tumours, we performe...
In order to identify new genes with differential expression in early intestinal tumours, we performe...
The Apc(Min/+) mouse has emerged as a powerful model of human intestinal tumour predisposition. As s...
BACKGROUND & AIMS: In colorectal cancer, activating mutations in the Wnt pathway transform epithelia...
BACKGROUND: Cancer results from the accumulation of mutations leading to the acquisition of cancer p...
Abstract: Background: Cancer results from the accumulation of mutations leading to the acquisition o...
In colorectal tumours, Wnt pathway genetics continues to be dominated by mutations in the adenomatou...
APC biallelic loss-of-function mutations are the most prevalent genetic changes in colorectal tumors...
Adenomatous polyposis coli (APC) mutations are found in most colorectal tumours. These mutations are...
Germline mutations in the adenomatous polyposis coli (APC) gene are responsible for familial adenoma...
Canonical wnt signaling is important in embryonic development and tumorigenesis of various tissues i...
Around 70 % of sporadic colorectal tumours show bi-allelic inactivation of the APC gene (Adenomatous...
Objective Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregul...
OBJECTIVE: Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregu...
The intestinal epithelium is a specialized simple epithelium that lines the gut and performs primary...