Background: Interstitial pneumonitis is an ill-defined side effect of sirolimus, a new immunosuppressant drug recently introduced for patients having organ transplantation. Objective: To evaluate clinical and laboratory features of sirolimus-associated pneumonitis. Design: Case series. Setting: 1 transplantation center in Paris, France. Patients: 24 patients who had renal transplantation and developed sirolimus-associated pneumonitis, including 8 patients previously re-ported. Measurements: Symptoms; laboratory tests, including broncho-alveolar fluid analysis; and computed tomography (CT) of the chest. Intervention: Withdrawal or dose reduction of sirolimus. Results: Clinical symptoms included cough (23 patients), fatigue (20 patients), fev...
Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome—a single-c...
Sirolimus-associated pneumonitis, a rare but serious drug-induced lung injury, has become a great co...
AbstractLike sirolimus, everolimus is an inhibitor of mTOR (mammalian target of rapamycin), used as ...
Lymphocytic alveolitis and radiologic bronchiolitis obliterans-organizing pneumonia were the key fin...
PURPOSE: Sirolimus is a potent immunosuppressive agent used with increasing frequency in kidney tran...
A 64 year-old man, who received a renal transplant in 1988 for end-stage renal disease due to chroni...
Item does not contain fulltextThe use of inhibitors of the mammalian target of rapamycin (mTORi) in ...
Goal of Case report: Presentation of PCP \u3e1-year post-transplant and role of prophylaxis and immu...
The use of inhibitors of the mammalian target of rapamycin (mTORi) in renal transplantation is assoc...
International audienceIntroductionSirolimus is an immunosupressant used in renal transplantation bec...
The mTOR inhibitors (mTORi, mammalian target of rapamycin; sirolimus and everolimus) have been recen...
AbstractObjectivesReport a case of sirolimus induced granulomatous pneumonitis.BackgroundSirolimus i...
BACKGROUND: Standard immunosuppression after lung transplantation includes calcineurin inhibitors, a...
Transpl Int. 2007 Mar;20(3):291-6. Pulmonary alveolar proteinosis: a rare pulmonary toxicity of s...
AbstractDrug induced lung diseases (DILD) are an increasingly cause of morbidity. Many drugs have be...
Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome—a single-c...
Sirolimus-associated pneumonitis, a rare but serious drug-induced lung injury, has become a great co...
AbstractLike sirolimus, everolimus is an inhibitor of mTOR (mammalian target of rapamycin), used as ...
Lymphocytic alveolitis and radiologic bronchiolitis obliterans-organizing pneumonia were the key fin...
PURPOSE: Sirolimus is a potent immunosuppressive agent used with increasing frequency in kidney tran...
A 64 year-old man, who received a renal transplant in 1988 for end-stage renal disease due to chroni...
Item does not contain fulltextThe use of inhibitors of the mammalian target of rapamycin (mTORi) in ...
Goal of Case report: Presentation of PCP \u3e1-year post-transplant and role of prophylaxis and immu...
The use of inhibitors of the mammalian target of rapamycin (mTORi) in renal transplantation is assoc...
International audienceIntroductionSirolimus is an immunosupressant used in renal transplantation bec...
The mTOR inhibitors (mTORi, mammalian target of rapamycin; sirolimus and everolimus) have been recen...
AbstractObjectivesReport a case of sirolimus induced granulomatous pneumonitis.BackgroundSirolimus i...
BACKGROUND: Standard immunosuppression after lung transplantation includes calcineurin inhibitors, a...
Transpl Int. 2007 Mar;20(3):291-6. Pulmonary alveolar proteinosis: a rare pulmonary toxicity of s...
AbstractDrug induced lung diseases (DILD) are an increasingly cause of morbidity. Many drugs have be...
Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome—a single-c...
Sirolimus-associated pneumonitis, a rare but serious drug-induced lung injury, has become a great co...
AbstractLike sirolimus, everolimus is an inhibitor of mTOR (mammalian target of rapamycin), used as ...