mutations were searched for in liver biopsy specimens from 58 Italian patients with chronic hepatitis C, and morphologic features were compared to examine their reciprocal relation and their contribution to disease progression. HDI was evident in 48 % of cases with features of nonhemochromatosis iron overload. Total, sinusoidal, and portal HDI increased with stage; grade was related to all iron scores because of the contribu-tion of portal inflammation and interface hepatitis. HFE mutations were seen in 47 % of patients with chronic hepatitis C and in 28 % of control subjects; they were related to stage and the His63Asp mutation to portal HDI. On multivariate analysis, grade but not stage or HFE mutations was associated with HDI in all site...
P. 79-83The objective of the present study was to determine the presence of hepatic iron overload in...
OBJECTIVE: Hepatic iron overload is observed in many forms of chronic liver disease. Hereditary hem...
The possible role of iron in facilitating the development of liver cancer is still debated. The aims...
Histologically detectable iron (HDI) and HFE mutations were searched for in liver biopsy specimens f...
Histologically detectable iron (HDI) and HFE mutations were searched for in liver biopsy specimens f...
Background Conflicting results have been reported in studies evaluating the relationship between ser...
INTRODUCTION: Chronic hepatitis C (CHC) is often associated with alterations in iron and lipid metab...
Background: Chronic hepatitis C is frequently associated with increased hepatic iron stores. It rema...
Hepatic iron has been described in hepatitis C virus (HCV) infection as an important cofactor of dis...
The objective of the present study was to determine the presence of hepatic iron overload in patient...
Increased hepatic iron content may be observed in patients with chronic hepatitis C infection, and m...
Background and Aims: Iron deposits in the liver and abnormalities in serum iron biochemistry are fre...
Background and Objectives Hepatitis C virus (HCV) chronic hepatitis predisposes to iron overload, wh...
Abstract BACKGROUND AND OBJECTIVES: Hepatitis C virus (HCV) chronic hepatitis predisposes to iro...
Genetic haemochromatosis is an autosomal recessive disorder due to excessive intestinal iron absorpt...
P. 79-83The objective of the present study was to determine the presence of hepatic iron overload in...
OBJECTIVE: Hepatic iron overload is observed in many forms of chronic liver disease. Hereditary hem...
The possible role of iron in facilitating the development of liver cancer is still debated. The aims...
Histologically detectable iron (HDI) and HFE mutations were searched for in liver biopsy specimens f...
Histologically detectable iron (HDI) and HFE mutations were searched for in liver biopsy specimens f...
Background Conflicting results have been reported in studies evaluating the relationship between ser...
INTRODUCTION: Chronic hepatitis C (CHC) is often associated with alterations in iron and lipid metab...
Background: Chronic hepatitis C is frequently associated with increased hepatic iron stores. It rema...
Hepatic iron has been described in hepatitis C virus (HCV) infection as an important cofactor of dis...
The objective of the present study was to determine the presence of hepatic iron overload in patient...
Increased hepatic iron content may be observed in patients with chronic hepatitis C infection, and m...
Background and Aims: Iron deposits in the liver and abnormalities in serum iron biochemistry are fre...
Background and Objectives Hepatitis C virus (HCV) chronic hepatitis predisposes to iron overload, wh...
Abstract BACKGROUND AND OBJECTIVES: Hepatitis C virus (HCV) chronic hepatitis predisposes to iro...
Genetic haemochromatosis is an autosomal recessive disorder due to excessive intestinal iron absorpt...
P. 79-83The objective of the present study was to determine the presence of hepatic iron overload in...
OBJECTIVE: Hepatic iron overload is observed in many forms of chronic liver disease. Hereditary hem...
The possible role of iron in facilitating the development of liver cancer is still debated. The aims...