BACKGROUND: Analysis of circulating immune com-plexes (CICs) produced during an immune response may be useful in elucidating some aspects of this pro-cess. Identification of antigens incorporated into CICs provides information that may be helpful in develop-ing diagnostic and treatment strategies for autoim-mune diseases, infection, cancer, and transplantation therapy, and such information might be more relevant than information on free antigens. Because CICs may contain many antigens, comprehensive identification and profiling of such antigens is more effective than immunoblotting detection. METHODS: We developed a novel proteomic strategy (immune complexome analysis) in which immune complexes (ICs) are separated from serum, digeste
Abstract Background Autoantibodies are produced when ...
Proteomics technologies are often used for the identification of protein targets of the immune syste...
Rheumatoid arthritis (RA) is a chronic, autoimmune and inflammatory joint disease with a poorly unde...
BACKGROUND: Analysis of circulating immune com-plexes (CICs) produced during an immune response may ...
Immune complexes (ICs) are produced during an immune response and may reflect some aspects of an ong...
Objective: Immune complexes (ICs) trigger humoral immune responses. Therefore, the identification of...
A novel approach to recover and identify immune complexes (ICs) was developed using size exclusion c...
SUMMARY Circulating immune complexes (CIC) were isolated from 25 patients with rheumatoid arthritis ...
The identification of antigens incorporated into immune complexes (IC-antigens) is important for stu...
ABSTRACT: Analysis of blood samples from patients suffering from autoim-mune diseases remains a main...
In many diseases (e.g. autoimmune diseases, cancer), a humoral immune response is thought to be invo...
Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular endothelial dysfunction ...
Deposits of Ig and complement are abundant in affected joints of patients with rheumatoid arthritis ...
Synovial fluids from 102 patients affected by various joint diseases have been analyzed for their pr...
We developed antigen-nonspecific enzyme-linked immunoassays (ELISA) to quantitate IgG-C3- and IgM-C3...
Abstract Background Autoantibodies are produced when ...
Proteomics technologies are often used for the identification of protein targets of the immune syste...
Rheumatoid arthritis (RA) is a chronic, autoimmune and inflammatory joint disease with a poorly unde...
BACKGROUND: Analysis of circulating immune com-plexes (CICs) produced during an immune response may ...
Immune complexes (ICs) are produced during an immune response and may reflect some aspects of an ong...
Objective: Immune complexes (ICs) trigger humoral immune responses. Therefore, the identification of...
A novel approach to recover and identify immune complexes (ICs) was developed using size exclusion c...
SUMMARY Circulating immune complexes (CIC) were isolated from 25 patients with rheumatoid arthritis ...
The identification of antigens incorporated into immune complexes (IC-antigens) is important for stu...
ABSTRACT: Analysis of blood samples from patients suffering from autoim-mune diseases remains a main...
In many diseases (e.g. autoimmune diseases, cancer), a humoral immune response is thought to be invo...
Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular endothelial dysfunction ...
Deposits of Ig and complement are abundant in affected joints of patients with rheumatoid arthritis ...
Synovial fluids from 102 patients affected by various joint diseases have been analyzed for their pr...
We developed antigen-nonspecific enzyme-linked immunoassays (ELISA) to quantitate IgG-C3- and IgM-C3...
Abstract Background Autoantibodies are produced when ...
Proteomics technologies are often used for the identification of protein targets of the immune syste...
Rheumatoid arthritis (RA) is a chronic, autoimmune and inflammatory joint disease with a poorly unde...