The role of human papillomaviruses (HPV) in dysplastic and malignant oral verrucous lesions is controversial since there is a wide range in the incidence of virus detection. This study used a multi-tiered method of HPV detection using DNA in-situ hybridisation (ISH) for low-and high-risk subtypes, consensus PCR, and HPV genotype analysis in archival tissue from 20 cases of dysplastic and malignant oral verrucous lesions. The biological significance of HPV DNA detection was assessed by p16 immunohistochemistry (IHC). While 1/7 carcinomas and 5/13 dysplasias contained HPV DNA by consensus PCR and genotype analysis, all specimens were negative for low- and high-risk HPV ISH and negative for p16 IHC. Results show that although high-risk HPV DNA...
The purpose of the present study was to estimate the frequency of HPV DNA in four groups of oral les...
BACKGROUND: Verrucous carcinoma is a slowly growing, well-differentiated neoplasm with a predilectio...
Studies on the involvement of the human papillomavirus (HPV) in initiation and progression of oral n...
ObjectiveThe etiology of oral verrucous carcinoma is unknown, and human papillomavirus ‘involvement’...
Evidence has accumulated in recent years that relates certain types of human papillomaviruses (HPV) ...
OBJECTIVE: Verrucous carcinoma (VC) is a rare subtype of squamous cell carcinoma, occurring mostly i...
Background: Human papillomavirus DNA (HPV DNA) and p16 and p53 protein expressions were investigated...
This study determined the presence of human papillomavirus (HPV) DNA in oral mucosa cells from 121 p...
The DNAs of human papillomavirus (HPV) types 4, 16 and 18 have been detected in biopsies of normal a...
Background: The human papillomaviruses (HPVs) are known to induce cutaneous and mucosal proliferatio...
BackgroundHuman papillomavirus (HPV) is the cause of a fraction of head and neck squamous cell carci...
The association between human papillomavirus (HPV) types and oral lesions has been shown in many stu...
Abstract. Background: Human papillomavirus DNA (HPV DNA) and p16 and p53 protein expressions were i...
The oral cavity is a common site for human papillomavirus (HPV) infection, however much is still unk...
BACKGROUND: The association between human papillomavirus (HPV) types and oral lesions has been shown...
The purpose of the present study was to estimate the frequency of HPV DNA in four groups of oral les...
BACKGROUND: Verrucous carcinoma is a slowly growing, well-differentiated neoplasm with a predilectio...
Studies on the involvement of the human papillomavirus (HPV) in initiation and progression of oral n...
ObjectiveThe etiology of oral verrucous carcinoma is unknown, and human papillomavirus ‘involvement’...
Evidence has accumulated in recent years that relates certain types of human papillomaviruses (HPV) ...
OBJECTIVE: Verrucous carcinoma (VC) is a rare subtype of squamous cell carcinoma, occurring mostly i...
Background: Human papillomavirus DNA (HPV DNA) and p16 and p53 protein expressions were investigated...
This study determined the presence of human papillomavirus (HPV) DNA in oral mucosa cells from 121 p...
The DNAs of human papillomavirus (HPV) types 4, 16 and 18 have been detected in biopsies of normal a...
Background: The human papillomaviruses (HPVs) are known to induce cutaneous and mucosal proliferatio...
BackgroundHuman papillomavirus (HPV) is the cause of a fraction of head and neck squamous cell carci...
The association between human papillomavirus (HPV) types and oral lesions has been shown in many stu...
Abstract. Background: Human papillomavirus DNA (HPV DNA) and p16 and p53 protein expressions were i...
The oral cavity is a common site for human papillomavirus (HPV) infection, however much is still unk...
BACKGROUND: The association between human papillomavirus (HPV) types and oral lesions has been shown...
The purpose of the present study was to estimate the frequency of HPV DNA in four groups of oral les...
BACKGROUND: Verrucous carcinoma is a slowly growing, well-differentiated neoplasm with a predilectio...
Studies on the involvement of the human papillomavirus (HPV) in initiation and progression of oral n...