of Weaned Male Albino Rats Fed on Processed Atlantic Horse Mackerel (Trachurus trachurus)

Trachurus trachurus (locally called kote) is a low cost table fish in south-west Nigeria. Study was conducted to determine the effect of processed kote on total triglycerides (TG) & cholesterol (Chol) in the serum as well as lactate dehydrogenase (LDH), creatinine (CRT), Chol and glucose (Gluc) in selected tissues of weaned male albino rats using standard methods. Chemical analyses were car-ried out on processed fillet; skin, head & bone (SHB) diets under standard conditions. 40 male rats were fed with processed fillet or SHB diets for 14 days to assay TG & Chol in serum as well as the activities of LDH & CRT in the heart, kidney, brain, spleen and small intestine; in addition to Chol and Gluc levels in the brain and liver. All data were subjected to analysis of variance by Duncan’s multiple range test. Results indicated that levels of serum triglycerides and total cholesterol, as well as LDH and Gluc in the liver, heart, kidney and brain were reduced (p < 0.05) in rats fed on test diets compared to the controls, but within accepted limit. Levels of LDH and CRT in the kidney