Rat brain (Na + K)-adenosine triphosphatase is inhibited by ethanol (EtOH) in vitro, the inhibition being greater in the presence of norepinephrine (NE). Enzyme preparations from EtOH-tolerant rats show less inhibition by EtOH in vitro and less sensitization by NE. To investigate the mechanism of these changes, the enzyme activity of brain microsomes from tolerant and sucrose-control rats was measured at temperatures from 1 0-40#{176}C. Preparations from nonwithdrawn and 24-hr with-drawn rats were studied in the absence of in vitro additions, and in the presence of 1 tM NE, 50 mM EtOH or 440 mM EtOH separately, and of 1 tM NE + 50 mM EtOH. From Arrhenius plots of the results, the transition temperature (Td) was calcu-lated by a method of s...
The study of the metabolism of ethyl alcohol in rats expoxsed to a cold environment was investigated...
As previously reported UChA rats (low ethanol consumer) develop tolerance to the narcotic effect of ...
Abstract — Nitnc oxide synthase (NOS), the enzyme with reduced nicotinamide-adenine dinucleotide pho...
Sensitivity to ethanol, temperature dependence of apparent K affinity and temperature dependence of ...
CNS (Na + K)-ATPase has been considered to be involved in the depressant action of ethanol, through ...
We have previously reported that UChA rats (genetically low ethanol consumer) develop tolerance to n...
The mechanisms which account for the diminished responsiveness (tolerance) of an individual to a dru...
Chronic ethanol exposure impairs all organs and systems. There is no complete animal model for human...
Effects of K, ethanol and norepinephrine on the binding kinetics of ouabain to (Na’,K’)-adenosine t,...
BACKGROUND: Acute ethanol (EtOH) exposure reduces the evoked release of vasopressin (AVP) and oxytoc...
Among several effects, ethanol (EtOH) interferes with membrane fluidity and lipid-protein interactio...
The fluidity of brain synaptosomal plasma membranes (5PM) from ethanol-treated mice and control mice...
The in vitro effects of ethanol (EtOH) on muscarinic receptor-stimulated phosphoinositide metabolism...
AbstractIt has been suggested that ethanol stimulates adenylate cyclase in vitro through an increase...
Plasma and brain catecholamines were measured during im-mobilization in rats which had or had not re...
The study of the metabolism of ethyl alcohol in rats expoxsed to a cold environment was investigated...
As previously reported UChA rats (low ethanol consumer) develop tolerance to the narcotic effect of ...
Abstract — Nitnc oxide synthase (NOS), the enzyme with reduced nicotinamide-adenine dinucleotide pho...
Sensitivity to ethanol, temperature dependence of apparent K affinity and temperature dependence of ...
CNS (Na + K)-ATPase has been considered to be involved in the depressant action of ethanol, through ...
We have previously reported that UChA rats (genetically low ethanol consumer) develop tolerance to n...
The mechanisms which account for the diminished responsiveness (tolerance) of an individual to a dru...
Chronic ethanol exposure impairs all organs and systems. There is no complete animal model for human...
Effects of K, ethanol and norepinephrine on the binding kinetics of ouabain to (Na’,K’)-adenosine t,...
BACKGROUND: Acute ethanol (EtOH) exposure reduces the evoked release of vasopressin (AVP) and oxytoc...
Among several effects, ethanol (EtOH) interferes with membrane fluidity and lipid-protein interactio...
The fluidity of brain synaptosomal plasma membranes (5PM) from ethanol-treated mice and control mice...
The in vitro effects of ethanol (EtOH) on muscarinic receptor-stimulated phosphoinositide metabolism...
AbstractIt has been suggested that ethanol stimulates adenylate cyclase in vitro through an increase...
Plasma and brain catecholamines were measured during im-mobilization in rats which had or had not re...
The study of the metabolism of ethyl alcohol in rats expoxsed to a cold environment was investigated...
As previously reported UChA rats (low ethanol consumer) develop tolerance to the narcotic effect of ...
Abstract — Nitnc oxide synthase (NOS), the enzyme with reduced nicotinamide-adenine dinucleotide pho...