Summary: We have developed a Mathematica applica-tion package to perform dynamic simulations of the red blood cell (RBC) metabolic network. The package relies on, and integrates, many years of mathematical modeling and biochemical work on red blood cell metabolism. The extensive data regarding the red blood cell metabolic net-work and the previous kinetic analysis of all the individual components makes the human RBC an ideal ‘model ’ sys-tem for mathematical metabolic models. The Mathematica package can be used to understand the dynamics and reg-ulatory characteristics of the red blood cell. Availability: The Mathematica package and an example file can be downloaded fro
Integrative analysis between dynamical modeling of metabolic networks and data obtained from high th...
We previously reported a computer model of the human erythrocyte [1], which has three major metaboli...
AbstractThe development of high-throughput technologies and the resulting large-scale data sets have...
AbstractThe human red blood cell (hRBC) metabolic network is relatively simple compared with other w...
The theoretical modeling and computational simulation of human red blood cells is of interest to res...
We have developed a computer software package for Macintosh to simulate the metabolism and hemoglobi...
<p>These data represent the simulated trajectories of red blood cell (RBC) through different microva...
The experimental investigation of the red cell over last three decades has accumulated an extensive ...
The human red blood cell (RBC) is a logical starting point for the development and application of sy...
Understanding biological evolution prompts for a detailed understanding of the realized phenotype. B...
Summary: We present Dynetica, a user-friendly simula-tor of dynamic networks for constructing, visua...
<p><i>Panel A</i>: Transition of enzymatic activities. Each enzymatic activity was represented as a ...
This research investigates the applicability of mathematical and computer procedures for the simula...
Abstract Background The development of high-throughput technologies capable of whole cell measuremen...
Motivation: Genome-scale metabolic network models have become an indispensable part of the increasin...
Integrative analysis between dynamical modeling of metabolic networks and data obtained from high th...
We previously reported a computer model of the human erythrocyte [1], which has three major metaboli...
AbstractThe development of high-throughput technologies and the resulting large-scale data sets have...
AbstractThe human red blood cell (hRBC) metabolic network is relatively simple compared with other w...
The theoretical modeling and computational simulation of human red blood cells is of interest to res...
We have developed a computer software package for Macintosh to simulate the metabolism and hemoglobi...
<p>These data represent the simulated trajectories of red blood cell (RBC) through different microva...
The experimental investigation of the red cell over last three decades has accumulated an extensive ...
The human red blood cell (RBC) is a logical starting point for the development and application of sy...
Understanding biological evolution prompts for a detailed understanding of the realized phenotype. B...
Summary: We present Dynetica, a user-friendly simula-tor of dynamic networks for constructing, visua...
<p><i>Panel A</i>: Transition of enzymatic activities. Each enzymatic activity was represented as a ...
This research investigates the applicability of mathematical and computer procedures for the simula...
Abstract Background The development of high-throughput technologies capable of whole cell measuremen...
Motivation: Genome-scale metabolic network models have become an indispensable part of the increasin...
Integrative analysis between dynamical modeling of metabolic networks and data obtained from high th...
We previously reported a computer model of the human erythrocyte [1], which has three major metaboli...
AbstractThe development of high-throughput technologies and the resulting large-scale data sets have...