Of Clots and Granulomas: Platelets are New Players in Immunity to Tuberculosis

Over a century and a half after their first observation under the microscope by the English anatomist and physiologist George Gulliver, platelets, named after their plate-like shape by the American pathologist James Wright in 1910 [1], are still intensively studied, not only in the context of hemostasis but also in that of host defense against microbial pathogens. Platelets are small anucleated cells de-rived from megakaryocytes and constitute 1 of the 3 cell types of the blood, with white blood cells (leukocytes) and red blood cells (erythrocytes). These cell