Add to ORKGObjective To establish an algorithm for first-trimester combined screening for trisomy 21 with biochemical testing from 7 to 14 weeks ’ gestation and ultrasound testing at 11–13 weeks. Methods This was a multicenter study of 886 pregnancies with trisomy 21 and 222 475 unaffected pregnancies with measurements of free β-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A) at 7–14 weeks ’ gestation. Multiple regression modeling of log-transformed marker values was used to produce log multiples of the median (MoM) values for PAPP-A and free β-hCG. The models included terms for the center attended and the machine use
Introduction. Aneuploidies are the major cause of perinatal death and early psychophysical disorder...
AbstractObjectiveTo analyze the performance of the first trimester Down syndrome screening in a sing...
Objective To investigate the potential utility of first trimester screening for Down syndrome using ...
Objective To establish an algorithm for first-trimester combined screening for trisomy 21 with bioch...
Background: Pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin (...
Objectives: The aim of the study was to analyze the correlation of multiples of the normal median of...
Objectives: The purpose of the study was to compare detection rates (DR) of FMF-certified and non-ce...
To evaluate the performance of a one-stop clinic for assessment of risk (OSCAR) for trisomy 21 by a ...
BACKGROUND: Screening for fetal chromosome abnor-malities in the first trimester includes analysis o...
In 42 cases of trisomy 13 at 10-14 weeks of gestation, compared with 947 controls, the median multip...
Objective To examine the effectiveness of first-trimester fetal trisomy 21 screening using a combina...
Screening for chromosomal anomalies in pregnancy is widely practiced throughout the world. Screening...
Objective: The aim of the study was to evaluate the significance of the maternal blood level of preg...
Objectives To examine the clinical utility of the first-trimester markers of aneuploidy in their abi...
To establish normative weight-adjusted models for the median levels of first trimester serum biomark...
Introduction. Aneuploidies are the major cause of perinatal death and early psychophysical disorder...
AbstractObjectiveTo analyze the performance of the first trimester Down syndrome screening in a sing...
Objective To investigate the potential utility of first trimester screening for Down syndrome using ...
Objective To establish an algorithm for first-trimester combined screening for trisomy 21 with bioch...
Background: Pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin (...
Objectives: The aim of the study was to analyze the correlation of multiples of the normal median of...
Objectives: The purpose of the study was to compare detection rates (DR) of FMF-certified and non-ce...
To evaluate the performance of a one-stop clinic for assessment of risk (OSCAR) for trisomy 21 by a ...
BACKGROUND: Screening for fetal chromosome abnor-malities in the first trimester includes analysis o...
In 42 cases of trisomy 13 at 10-14 weeks of gestation, compared with 947 controls, the median multip...
Objective To examine the effectiveness of first-trimester fetal trisomy 21 screening using a combina...
Screening for chromosomal anomalies in pregnancy is widely practiced throughout the world. Screening...
Objective: The aim of the study was to evaluate the significance of the maternal blood level of preg...
Objectives To examine the clinical utility of the first-trimester markers of aneuploidy in their abi...
To establish normative weight-adjusted models for the median levels of first trimester serum biomark...
Introduction. Aneuploidies are the major cause of perinatal death and early psychophysical disorder...
AbstractObjectiveTo analyze the performance of the first trimester Down syndrome screening in a sing...
Objective To investigate the potential utility of first trimester screening for Down syndrome using ...