Background: Multiparity and breast-feeding reduce breast cancer risk, whereas oral contraceptive use may slightly increase breast cancer risk in the general population. However, the effects of these factors in BRCA1 and BRCA2 mutation carriers are less clear. Methods: Case patients were 1,469 women from Los Angeles County ages 20 to 49 years with newly diagnosed breast cancer. Control subjects were 444 women without breast cancer, individually matched to a subset of cases on race, age, and neighborhood. BRCA1/2 genes were sequenced in the cases, and odds ratios of breast cancer associated with various repro-ductive and hormonal factors in BRCA1/2 mutation carriers and noncarriers were estimated using multi
This study was conducted to identify the role of reproductive factors as environmental modifiers for...
BACKGROUND: Multiparity, young age at first childbirth, and breast-feeding are associated with a red...
The potential effects of oral contraceptive (OC) and postmenopausal hormone (PMH) use are not well u...
Background: Oral contraceptive use has been associated with an increase in the risk of breast cancer...
Purpose Earlier studies have shown that endogenous gonadal hormones play an important role in the et...
Background: BRCA1 and BRCA2 mutation carriers are at high risk of breast and ovarian cancer. Oral co...
Background: Women with BRCA1 or BRCA2 mutations are at increased risk of breast and ovarian cancer. ...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepara...
<p>Background: Several reproductive and hormonal factors are known to be associated with ovari...
Background: Women with deleterious mutations in BRCA genes are at increased risk of breast cancer. H...
Background: Several reproductive and hormonal factors are known to be associated with ovarian cancer...
This study was conducted to identify the role of reproductive factors as environmental modifiers for...
BACKGROUND: Multiparity, young age at first childbirth, and breast-feeding are associated with a red...
The potential effects of oral contraceptive (OC) and postmenopausal hormone (PMH) use are not well u...
Background: Oral contraceptive use has been associated with an increase in the risk of breast cancer...
Purpose Earlier studies have shown that endogenous gonadal hormones play an important role in the et...
Background: BRCA1 and BRCA2 mutation carriers are at high risk of breast and ovarian cancer. Oral co...
Background: Women with BRCA1 or BRCA2 mutations are at increased risk of breast and ovarian cancer. ...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepar...
Background For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive prepara...
<p>Background: Several reproductive and hormonal factors are known to be associated with ovari...
Background: Women with deleterious mutations in BRCA genes are at increased risk of breast cancer. H...
Background: Several reproductive and hormonal factors are known to be associated with ovarian cancer...
This study was conducted to identify the role of reproductive factors as environmental modifiers for...
BACKGROUND: Multiparity, young age at first childbirth, and breast-feeding are associated with a red...
The potential effects of oral contraceptive (OC) and postmenopausal hormone (PMH) use are not well u...