Angiogenesis, Metastasis, and the Cellular Microenvironment CADPE Inhibits PMA-Stimulated Gast Invasion and Matrix Metalloproteinase

Metastasis is one of the main causes of death for patie matrix metalloproteinase-9 (MMP-9) has been implicated Here, we found that caffeic acid 3,4-dihydroxy-phenethyl vasion of human gastric carcinoma cells in Transwell mig phorb ent m MP mob of th PE i dhesio EK) kinase hibits actor. Gastric death an The curre in western dence is a (2-4). Be prognosis clinical ch and meta patients. carcinom h nodes, c sites. It f matrix esses (6). s, which eir sub-agenase, MMPs Ps have e devel-owever, diseases, arthritis; genesis portant cluding (gelatinase-A) and MMP-9 (gelatinase-B) are key enzymes n, and metastasis d expression of with the progres-MP-2 is usuall