Ten-year Survival by Race/Ethnicity and Sex Among Treated, HIV-infected Adults in the

Background. Ensuring equal access to antiretroviral therapy (henceforth therapy) should alleviate disparities in health outcomes among persons infected with human immunodeficiency virus (HIV). However, evidence support-ing the persistence of disparities in survival following therapy initiation is mixed. Methods. Patients initiating therapy in eight academic medical centers in the Centers for AIDS Research Net-work of Integrated Clinical Systems between 1 January 1998 and 30 December 2011. Patients (n = 10 017) were fol-lowed from therapy initiation until death from any cause, administrative censoring at 10 years after therapy initiation or the end of follow-up on 31 December 2011. The 10-year risk of all-cause mortality was calculated from standard-ized Kaplan–Meier survival curves. Results. Patients were followed for a median of 4.7 years (interquartile range: 2.2, 8.2). During 51 121 person-years of follow-up, 1224 of the 10 017 patients died. The overall 10-year mortality risk was 20.2 % (95 % confidence interval [CI], 19.2%, 21.3%). Black men and women experienced standardized 10-year all-cause mortality risks that were 7.2 % (95 % CI, 4.3%, 10.1%) and 7.9 % (95 % CI, 3.9%, 12.0%) larger (absolute difference) than white men. White women, Hispanic men, and Hispanic women all had lower 10-year mortality than white men. Conclusions. These data serve as a call to action to identify modifiable mechanisms leading to these observe