Add to ORKGDiagnosis and management of the neuroinflammatory diseases of the central nervous system (CNS) are hindered by the lack of reliable biomarkers of active intrathecal inflammation. We hypothesized that measuring several putative inflammatory biomarkers simultaneously will augment specificity and sensitivity of the biomarker to the clinically useful range. Based on our pilot experiment in which we measured 18 inflammatory biomarkers in 10-fold concentrated cerebrospinal fluid (CSF) derived from 16 untreated patients with highly active multiple sclerosis (MS) we selected a combination of three CS
© 2017 Khaibullin, Ivanova, Martynova, Cherepnev, Khabirov, Granatov, Rizvanov and Khaiboullina.Mult...
Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between d...
Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between d...
<div><p>Diagnosis and management of the neuroinflammatory diseases of the central nervous system (CN...
BACKGROUND: Cytokines play multiple roles during neuro-inflammatory processes and several cytokines ...
Background: Diagnosis of multiple sclerosis (MS) is established on criteria according to clinical an...
Effective biomarkers for multiple sclerosis diagnosis, assessment of prognosis, and treatment respon...
BACKGROUND: Despite the discovery of CSF and serum diagnostic autoantibodies in autoimmune encephali...
BACKGROUND:Despite the discovery of CSF and serum diagnostic autoantibodies in autoimmune encephalit...
BackgroundThe recognition of active inflammation in the central nervous system (CNS) in the absence ...
BACKGROUND: Interleukin (IL)-6 is recognised as an important cytokine involved in inflammatory disea...
Meningeal inflammation, including the presence of semi-organized tertiary lymphoid tissue, has been ...
BACKGROUND: Subtle diffuse intrathecal inflammation is undetectable by conventional neuroimaging, a...
Background: Interleukin (IL)-6 is recognised as an important cytokine involved in inflammatory disea...
Inflammatory mediators have crucial roles in leukocyte recruitment and subsequent central nervous sy...
© 2017 Khaibullin, Ivanova, Martynova, Cherepnev, Khabirov, Granatov, Rizvanov and Khaiboullina.Mult...
Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between d...
Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between d...
<div><p>Diagnosis and management of the neuroinflammatory diseases of the central nervous system (CN...
BACKGROUND: Cytokines play multiple roles during neuro-inflammatory processes and several cytokines ...
Background: Diagnosis of multiple sclerosis (MS) is established on criteria according to clinical an...
Effective biomarkers for multiple sclerosis diagnosis, assessment of prognosis, and treatment respon...
BACKGROUND: Despite the discovery of CSF and serum diagnostic autoantibodies in autoimmune encephali...
BACKGROUND:Despite the discovery of CSF and serum diagnostic autoantibodies in autoimmune encephalit...
BackgroundThe recognition of active inflammation in the central nervous system (CNS) in the absence ...
BACKGROUND: Interleukin (IL)-6 is recognised as an important cytokine involved in inflammatory disea...
Meningeal inflammation, including the presence of semi-organized tertiary lymphoid tissue, has been ...
BACKGROUND: Subtle diffuse intrathecal inflammation is undetectable by conventional neuroimaging, a...
Background: Interleukin (IL)-6 is recognised as an important cytokine involved in inflammatory disea...
Inflammatory mediators have crucial roles in leukocyte recruitment and subsequent central nervous sy...
© 2017 Khaibullin, Ivanova, Martynova, Cherepnev, Khabirov, Granatov, Rizvanov and Khaiboullina.Mult...
Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between d...
Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between d...