CYTOCHROME OXIDASE AND CYTOCHROME

Since there appear to be at least four papers to be presented in this Symposium which must, more or less directly, be concerned with the subject of cytochrome oxidase and cytochrome, I have at-tempted in half of this paper only to briefly de-scribe the subject, and in the second half to describe in more detail the results of personal re-searches. In this way I hope the later papers will amplify my introduction and possibly avoid undue repetition. Although as early as 1887, MacMunn (1) ap-parently observed and separated from muscle the substance now known as cytochrome-c, the inter-est in iron as a cellular respiratory catalyst was aroused only in 1924 by Warburg (2). Upon ob