Add to ORKGAbstract — Radiation therapy for cancers of the head and neck can irreversibly damage the salivary glands. Xerostomia (subjective oral dryness) develops within the first week of therapy and is progressive, with devastating effects on the quality of life of the individual. The xerostomia does not correlate with the degree of salivary gland hypofunction. The mechanism of tissue injury in humans is still unclear, but much progress has been made with animal models. This paper reviews the natural history of radiation damage to human salivary glands and highlights the inter-individual variations in the responses to and recovery from therapeutic radiation. The degree of salivary gland damage is correlated to the dose of radiation delivered and the...
The most significant long-term complication of radiotherapy in the head-and-neck region is hyposaliv...
Each year, 500,000 patients are treated with radiotherapy for head and neck cancer, resulting in rel...
Saliva has a critical role in the maintenance of oral, dental and general health and well-being. Alt...
BACKGROUND: The most manifest long-term consequences of radiation therapy in the head and neck cance...
The most significant long-term complication of radiotherapy in the head-and-neck region is hyposaliv...
Saliva is produced by and secreted from salivary glands. It is an extra-cellular fluid, 98% water, p...
Purpose: To contribute to the understanding of the enigmatic radiosensitivity of the salivary glands...
Dry mouth or xerostomia is the most frequently observed side-effect of radiotherapy (RT) in the head...
Radiotherapy is a common treatment for head and neck cancer patients. Unfortunately, it produces ser...
The introduction of intensity-modulated radiotherapy treatment has produced a small surplus of treat...
Radiation-induced hyposalivation is still a major problem after radiotherapy for head and neck cance...
The most significant long-term complication of radiotherapy in the head-and-neck region is hyposaliv...
Each year, 500,000 patients are treated with radiotherapy for head and neck cancer, resulting in rel...
Saliva has a critical role in the maintenance of oral, dental and general health and well-being. Alt...
BACKGROUND: The most manifest long-term consequences of radiation therapy in the head and neck cance...
The most significant long-term complication of radiotherapy in the head-and-neck region is hyposaliv...
Saliva is produced by and secreted from salivary glands. It is an extra-cellular fluid, 98% water, p...
Purpose: To contribute to the understanding of the enigmatic radiosensitivity of the salivary glands...
Dry mouth or xerostomia is the most frequently observed side-effect of radiotherapy (RT) in the head...
Radiotherapy is a common treatment for head and neck cancer patients. Unfortunately, it produces ser...
The introduction of intensity-modulated radiotherapy treatment has produced a small surplus of treat...
Radiation-induced hyposalivation is still a major problem after radiotherapy for head and neck cance...
The most significant long-term complication of radiotherapy in the head-and-neck region is hyposaliv...
Each year, 500,000 patients are treated with radiotherapy for head and neck cancer, resulting in rel...
Saliva has a critical role in the maintenance of oral, dental and general health and well-being. Alt...