DOI: 10.1177/1932296814522747

dst.sagepub.com Letter to the Editor Continuous insulin infusion (CII) protocols with glycemic targets 110-140 mg/dl are suggested following cardiac sur-gery in patients with and without diabetes provided that these targets can be achieved with low risk for moderate (MH) and severe (SH) hypoglycemia.1-4 The purpose of this investiga-tion was to investigate differences in efficacy and safety of these targets according to diabetes status. Glycemic data were collected from 247 consecutive patients treated with 1 of 2 published CII protocols (P1 and P2) targeting blood glucose (BG) 110-140 mg/dl for ≤48 hours following cardiac surgery.5 Diabetes status was defined by medical record documentation or preoperative A1c ≥ 6.5%.6 Protocol efficacy was measured by time to BG target