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In this research, ozone hydrodynamics and disinfection by-products formation in a novel hybrid ozonation-ceramic membrane filtration system was studied to minimize membrane fouling while also ensuring that the system meets regulatory criteria for disinfection by-products. The influence of important operating parameters including inlet ozone mass injection rate, initial bromide concentration, membrane molecular weight cut off (MWCO), membrane coating, hydroxyl radical scavenger (t-butanol), pH, and temperature on bromate concentration in the absence and presence of natural organic matter (NOM) was examined. Experiments were also conducted under various operating conditions to investigate the formation of total trihalomethanes (TTHMs) and halo-acetic acids (HAAs) in the water distribution system due to post chlorination. Moreover, variations in the TOC, UV254, color and turbidity with respect to operating parameters were monitored. Bromate and TTHMs formation increased with increasing ozone mas