Study Objective: To determine whether beta-adrenergic blockade augments cocaine-induced coronary artery vasoconstriction. Design: Randomized, double-blind, placebo-controlled trial. Setting: A cardiac catheterization laboratory in an urban teach-ing hospital. Patients: Thirty clinically stable patient volunteers referred for catheterization for evaluation of chest pain. Interventions: Heart rate, arterial pressure, coronary sinus blood flow (by thermodilution), and epicardial left coronary arterial dimensions were measured before and 15 minutes after intranasal saline or cocaine administration (2 mg/kg body weight) and again after intracoronary propranolol administration (2 mg in 5 minutes). Measurements and Main Results: No variables chang...
The purpose of this study was to determine the effects of cocaine on vasoreactivity in the swine mod...
Cardiac complications resulting from cocaine use have been extensively studied because of the compli...
Introduction Cocaine is the second most commonly used illicit drug in the United States, 1 and is th...
AbstractThis study investigated the effect of intravenous cocaine (0.5 to 2 mg/kg body weight) on th...
ObjectivesThe aim of this study was to determine whether cocaine’s sympathomimetic actions can be re...
AbstractIntranasal cocaine, 2 to 3 mg/kg body weight, is a commonly used local anesthetic for rhinol...
Background. The effects of cocaine on the coronary circulation were examined in conscious dogs chron...
cocaine-induced coronary vasoconstriction in humans and to assess the relation between cocaine-induc...
The most common symptom of cocaine abuse is chest pain. Cocaine induced chest pain (CICP) shares pat...
AbstractCocaine increases myocardial oxygen demand and paradoxically decreases oxygen supply by redu...
Background—In dogs, a large amount of intravenous cocaine causes a profound deterioration of left ve...
AbstractBackgroundThe most common symptom of cocaine abuse is chest pain. Cocaine induced chest pain...
Long-term cocaine use, as well as acute cocaine use, is associated with adverse cardiovascular conse...
Objectives.This study sought to assess endothelium-dependent vasorelaxation in long-term users of co...
AbstractObjectives. The goal of this study was to define in vivo the magnitude and temporal course o...
The purpose of this study was to determine the effects of cocaine on vasoreactivity in the swine mod...
Cardiac complications resulting from cocaine use have been extensively studied because of the compli...
Introduction Cocaine is the second most commonly used illicit drug in the United States, 1 and is th...
AbstractThis study investigated the effect of intravenous cocaine (0.5 to 2 mg/kg body weight) on th...
ObjectivesThe aim of this study was to determine whether cocaine’s sympathomimetic actions can be re...
AbstractIntranasal cocaine, 2 to 3 mg/kg body weight, is a commonly used local anesthetic for rhinol...
Background. The effects of cocaine on the coronary circulation were examined in conscious dogs chron...
cocaine-induced coronary vasoconstriction in humans and to assess the relation between cocaine-induc...
The most common symptom of cocaine abuse is chest pain. Cocaine induced chest pain (CICP) shares pat...
AbstractCocaine increases myocardial oxygen demand and paradoxically decreases oxygen supply by redu...
Background—In dogs, a large amount of intravenous cocaine causes a profound deterioration of left ve...
AbstractBackgroundThe most common symptom of cocaine abuse is chest pain. Cocaine induced chest pain...
Long-term cocaine use, as well as acute cocaine use, is associated with adverse cardiovascular conse...
Objectives.This study sought to assess endothelium-dependent vasorelaxation in long-term users of co...
AbstractObjectives. The goal of this study was to define in vivo the magnitude and temporal course o...
The purpose of this study was to determine the effects of cocaine on vasoreactivity in the swine mod...
Cardiac complications resulting from cocaine use have been extensively studied because of the compli...
Introduction Cocaine is the second most commonly used illicit drug in the United States, 1 and is th...