111 PUBLICATIONS 1,144 CITATIONS SEE PROFILE

Cardiovascular disease (CVD) is a leading cause of mor-tality in renal transplant recipients (RTRs). Metabolic syndrome (MS) is highly prevalent in RTRs. Nonalco-holic fatty liver disease (NAFLD) is considered the hep-atic component of MS. We investigated associations of NAFLD markers with MS and mortality. RTRs were investigated between 2001 and 2003. NAFLD mark-ers, alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT) and alkaline phosphatase (AP) were measured. Bone and nonbone fractions of AP were also determined. Death was recorded until August 2007. Six hundred and two RTRs were studied (age 52 ± 12 years, 55 % men). At baseline 388 RTRs had MS. Prevalence of MS was positively associated with liver enzymes. Dur-ing follow-up for 5.3[4.5–5.7] years, 95 recipients die