A Practical Method for Decreasing the Serum Cholesterol Level in Man12

disease is often considered to be re-lated to the height of the serum cholesterol level, and many trials have been and are being carried out to reduce serum choles-terol levels by dietary measures both in pa-tients and in healthy subjects (1-5), it was thought worthwhile to study the effects of such a simple dietary measure so that it could be followed by everybody. Only a procedure causi ng minimal disturbance to the household can be seen as a successful one for many patients in the long run, and only such a procedure could be used as a preventive on a large scale. Such a measure could be an appropriate change in the dietary fat composition. An increase in the polyunsaturated fatty acid content of margarine would be largely sufficient for the latter purpose since its consumption is high as a biead spread as well as a cooking fat, and it can replace butter and other cooking fats. A trial was set up, therefore, to learn whether a decrease of the serum cholesterol levels could be achieved by supplying suc