Complete Genome Sequence of Klebsiella oxytoca E718, a New Delhi

We report the complete genome sequence of Klebsiella oxytoca E718, a New Delhi metallo--lactamase-1 (NDM-1)-producing strain isolated from a renal transplant patient. The genome contains a 6,097,032-bp chromosome and twomultidrug resistance plasmids with sizes of 324,906 bp and 110,781 bp. Klebsiella oxytoca is a member of the Enterobacteriaceae and thesecond-most-common Klebsiella species recovered in clinical medicine. It is an important opportunistic pathogen that can cause various nosocomial and community infections, including septicemia, pneumonia, urinary tract infection, and antibiotic-associated hemorrhagic colitis (4, 8). Carbapenems such as imipenem andmeropenem are the drugs of last resort for treat-ing infections caused by extended-spectrum--lactam-resis-tant Gram-negative bacteria. As a consequence, the emergence of carbapenem-resistant strains, particularly Escherichia coli and Klebsiella pneumoniae, has become a worldwide problem (6, 7). Although present to a lesser extent, several important carbap-enemases, including K. pneumoniae carbapenemase (KPC) an