Add to ORKGNatalizumab is a humanized monoclonal antibody that binds the cellular adhesion molecule α4-integrin. It blocks the migration of leucocytes into the central nervous system (CNS) and thus, reduce
In the early 1990s, attention was drawn to the migration of immune cells into the central nervous sy...
As Blood-brain barrier (BBB) breakdown is central to inflammatory lesion formation, it presents a po...
Inhibiting the alpha(4) subunit of the integrin heterodimers alpha(4)beta(1) and alpha(4)beta(7) wit...
Natalizumab is a humanized monoclonal antibody that binds the cellular adhesion molecule α4-integrin...
Natalizumab (NTZ) is a humanized anti-α4 integrin monoclonal antibody approved for relapsing–remitti...
In 1992, it was shown that monoclonal antibodies blocking alpha(4)-integrins prevent the development...
Integrins are the foremost family of cell adhesion molecules that regulate immune cell trafficking i...
The humanized anti-alpha(4) integrin Ab Natalizumab is an effective treatment for relapsing-remittin...
Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system. It is charact...
Natalizumab is a monoclonal antibody directed against the \u3b14 chain of the very late activating a...
Copyright © 2012 Eiji Kawamoto et al. This is an open access article distributed under the Creative ...
In the early 1990s, attention was drawn to the migration of immune cells into the central nervous sy...
Natalizumab is a humanized monoclonal antibody with a selective adhesion-molecule inhibitor effect, ...
Natalizumab is a recombinant monoclonal antibody raised against integrin alpha-4 (CD49d). It is appr...
Natalizumab, an antibody against the α4 subunit of α4 integrins, has been approved for multiple scle...
In the early 1990s, attention was drawn to the migration of immune cells into the central nervous sy...
As Blood-brain barrier (BBB) breakdown is central to inflammatory lesion formation, it presents a po...
Inhibiting the alpha(4) subunit of the integrin heterodimers alpha(4)beta(1) and alpha(4)beta(7) wit...
Natalizumab is a humanized monoclonal antibody that binds the cellular adhesion molecule α4-integrin...
Natalizumab (NTZ) is a humanized anti-α4 integrin monoclonal antibody approved for relapsing–remitti...
In 1992, it was shown that monoclonal antibodies blocking alpha(4)-integrins prevent the development...
Integrins are the foremost family of cell adhesion molecules that regulate immune cell trafficking i...
The humanized anti-alpha(4) integrin Ab Natalizumab is an effective treatment for relapsing-remittin...
Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system. It is charact...
Natalizumab is a monoclonal antibody directed against the \u3b14 chain of the very late activating a...
Copyright © 2012 Eiji Kawamoto et al. This is an open access article distributed under the Creative ...
In the early 1990s, attention was drawn to the migration of immune cells into the central nervous sy...
Natalizumab is a humanized monoclonal antibody with a selective adhesion-molecule inhibitor effect, ...
Natalizumab is a recombinant monoclonal antibody raised against integrin alpha-4 (CD49d). It is appr...
Natalizumab, an antibody against the α4 subunit of α4 integrins, has been approved for multiple scle...
In the early 1990s, attention was drawn to the migration of immune cells into the central nervous sy...
As Blood-brain barrier (BBB) breakdown is central to inflammatory lesion formation, it presents a po...
Inhibiting the alpha(4) subunit of the integrin heterodimers alpha(4)beta(1) and alpha(4)beta(7) wit...