An Analysis of the Global and Partial Voice Handicap Index in Patients with Early Glottic Carcinoma Treated with High Level of Irradiation

Copyright © 2014 Daniela Musio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In accor-dance of the Creative Commons Attribution License all Copyrights © 2014 are reserved for SCIRP and the owner of the intellectual property Daniela Musio et al. All Copyright © 2014 are guarded by law and by SCIRP as a guardian. Background: This is a retrospective study on a group of patients with early glottic carcinoma, treated with cura-tive radiotherapy. The aim of the study is to assess voice quality after treatment. We also evaluated local recur-rence, overall survival, disease free survival and toxicity. Material and Methods: We examined a total of 36 pa-tients, out of which 27 were smokers: 10 females/5 smokers; 26 males/22 smokers. The sample was observed from January 2007 to July 2012 (average follow-up period: 33.5 months, range 12- 76). Diagnosis of early glottic car-cinoma was eight during the two-year period 2007/2008, nine during 2009/2010, eleven during year 2011 and eight during year 2012. All patients suffering from early glottic carcinoma, histopathologically confirmed, were classified as follows: 24 patients T1a, 3 patients T1b, 6 patients T2 and 3 patients had a carcinoma in situ. The